| Emilio
Herrera
Current position:
- Professor of Biochemistry and Molecular Biology, Faculty of Experimental
and Health Sciences, University San Pablo-CEU, Madrid, Spain.
Academic and research activities:
- Master in Pharmacy, 1962.
- Doctor (PhD) by Complutense University in Madrid, 1965.
- Postdoctorate in USA (1965-68): Harvard University Medical School,
Boston, and Northwestern University Medical School, Chicago.
- Investigator of the Spanish Research Council, 1968-1969.
- Assistant Professor of Animal Physiology, School of Biology, Complutense
University of Madrid (1969-71).
- Professor of General Physiology, School of Biology, Barcelona
University (1972-78).
- Head of the Biochemical Service, Department of Research, Hospital
Ramón y Cajal, Madrid (1978-1994).
- Chairman of the Department of Research, and General Research
Coordinator of Hospital Ramón y Cajal, Madrid (1982-1994).
- Professor of Biochemistry and Molecular Biology, School of Medicine,
Alcalá de Henares University (1982-93), and University of
San Pablo-CEU, from 1994.
- Dean, Faculty of Experimental and Health Sciences, University
of San Pablo-CEU, 1994-1998.
Prizes and research distinctions:
- Award of the Spanish Red Cross for Diabetological Research, 1971.
- Research Award Leandre Cervere, 1975.
- National LEO prize for Diabetological Research, 1976.
- National LEO prize for Diabetological Research, 1978.
- First Novo-Nordisk prize for Basic Research in Diabetes, Spanish
Diabetes Society, 1990.
- Institute Danone prize on the Scientific Trajectory, 1996.
- Doctor Honoris Causa en Medicina from Lund University, Sweden,
1995.
- Research award of Fundación San Pablo-CEU, 1999
PhD theses supervised:
43
Publications:
- In scientific journals and book chapters: 345
- Editor of 6 books
- Presentations to Scientific Congresses (Abstracts): 578
Other appointments and distinctions:
- Coordinator of the Perinatal Biochemistry Group, Spanish Society
of Biochemistry and Molecular Biology from 1978.
- President of the National Clinical Biochemistry Council (from1993),
Ministries of Health and of Education and Culture of Spain.
- President of the Spanish Pharmaceutical Specialties Council
(from 1996), Ministries of Health and of Education and Culture
of
Spain.
- Chairman of the European Diabetes Pregnancy Study Group of the
European Diabetes Association, 1997-1998.
Current Scientific Projects
-
see separate page by clicking here
Scientific publications
- Herrera, E., F. Escobar del Rey, and G. Morreale de Escobar.
Effect of propylthyuracil on the in vivo deiodination of
thyroxyne labeled with I131 in different positions. Endocrinology
73: 744-747, 1963.
- Herrera, E. Interferencias
en el catabolismo de las hormonas tiroideas y sus consecuencias
metabólicas. Madrid, PhD
Thesis, Universidad Complutense de Madrid. 1965.
- Herrera, E., F. Escobar del Rey, and G. Morreale de Escobar.
Mechanism of goitrogenesis by very low propylthiouracil doses
and the role of iodine intake. In: Intern.Thyroid Conference,
ed. Current topics in thyroid research. New York, Academic Press.
1965, 259-270.
- Herrera, E. and N. Freinkel. Internal standards in the estimation
of acetyl-CoA in liver extracts. J.Lipid Res. 8: 515-518, 1967.
- Herrera, E., G. Morreale de Escobar, and F. Escobar del Rey.
Different effect of methylmercaptoimidazole and propylthiouracil
on thyroidal I131 release in rats on Cl0-4.
Endocrinology 83: 671-677, 1968.
- Herrera, E. and N. Freinkel. Interrelationships between liver
composition, plasma glucose and ketones and hepatic acetyl-CoA
and citric acid during prolonged starvation in the male rat. Biochim.Biophys.Acta
170: 244-253, 1968.
- Herrera, E., F. Escobar del Rey, and G. Morreale de Escobar.
Mechanism of goitrogenesis by very low doses of propylthiouracil
and the role of iodine intake. Acta Endocrinol.(Copenh.) 59: 529-544,
1968.
- Herrera, E., R. H. Knopp, and N. Freinkel. Urinary excretion
of epinephrine and norepinephrine during fasting in late pregnancy
in the rat. Endocrinology 84: 447-450, 1969.
- Herrera, E., R. H. Knopp, and N. Freinkel. Carbohydrate metabolism
in pregnancy VI. Plasma fuels, insulin, liver composition, gluconeogenesis
and nitrogen metabolism during gestation in the fed and fasted
rat. J.Clin.Invest. 48: 2260-2272, 1969.
- Castro, M., L. Lamas, and E. Herrera. Efecto de deficiencia
de hormonas tiroideas sobre el metabolismo intermediario en la
rata. Bol.Soc.Cien.Fisiol. 12: 311-313, 1970.
- Freinkel, N., E. Herrera, R. H. Knopp, and H. J. Ruder. Metabolic
realignments in late pregnancy: a clue to diabetogenesis. In Camarini
Davalos, R. and H. S. Cole, eds. Early diabetes. New York, Academic
Press. 1970, 205-215.
- Freinkel, N., B. Metzger, E. Herrera, F. Agnoli, and R. H.
Knopp. The effects of pregnancy on metabolic fuels. Excepta Med.Int.Cong.Sec.
231: 656-666, 1970.
- Herrera, E., R. H. Knopp, and N. Freinkel. Estudio metabólico
del tejido adiposo en la rata preñada. Bol.Soc.Cien.Fisiol.
12: 361-363, 1970.
- Herrera, E. and L. Lamas. Utilization of glycerol by rat adipose
tissue in vitro. Biochem.J. 120: 433-434, 1970.
- Herrera, E. Metabolismo intermediario en obesidad y diabetes
experimental. Jorn.Diabetol. 3: 98-104, 1970.
- Knopp, R. H., E. Herrera, and N. Freinkel. Carbohydrate metabolism
in pregnancy.VIII. Metabolism of adipose tissue isolated from
fed and fasted pregnant rats during late gestation. J.Clin.Invest.
49: 1438-1446, 1970.
- Knopp, R. H., H. J. Ruder, E. Herrera, and N. Freinkel. Carbohydrate
metabolism in pregnancy VII. Insulin tolerance during late pregnancy
in the fed and fasted rat. Acta Endocrinol.(Copenh) 65: 352-360,
1970.
- Schiaffini, O., E. Herrera, and A. Gallego. Producción
in vitro de C1402
a partir de D-glucosa-1-C14
y D-glucosa-6-C14 por distintas
áreas del hipotálamo, sistemas límbico e
hipófisis de rata hembra en diferentes etapas del ciclo
sexual. Rev.Esp.Fisiol. 26: 27-30, 1970.
- Blázquez, E., M. Castro, and E. Herrera. Effect of a
high-fat diet on pancreatic insulin release, glucose tolerance
and hepatic gluconeogenesis in male rats. Rev.Esp.Fisiol. 27:
297-304, 1971.
- Blázquez, E., M. Castro, and E. Herrera. Factores diabetogénicos
de la dieta rica en grasa. Diabetol.Clin.Endocr.Nutr. 6: 41-52,
1971.
- Aranda, A., E. Blázquez, and E. Herrera. Effects of hypo
and hyperthyroidism on liver composition, blood glucose, ketone
bodies and insulin in the male rat. Biochem.J. 128: 597-604, 1972.
- Castro, M., L. Lamas, and E. Herrera. Thyroid funtion, plasma
insulin, glucose and ketones and in vitro hepatic gluconeogenesis
in rats under chronic low iodine intake. Acta Endocrinol.(Copenh.)
69: 1-12, 1972.
- Herrera, E. and A. Ayanz. Calculation of lipolysis and esterification
from glycerol metabolism in rat adipose tissue. J.Lipid Res. 13:
802-809, 1972.
- Herrera, E. and R. H. Knopp. Pentose monophosphate shunt dehydrogenases
and fatty acid synthesis in late rat pregnancy. Experientia 28:
646-647, 1972.
- Aranda, A., E. Blázquez, and E. Herrera. Liver components,
blood glucose and ketone bodies in fed and starved suckling rats.
Horm.Metabol.Res. 5: 350-355, 1973.
- Castro, M. and E. Herrera. Effect of thyroidectomy on circulating
components and liver metabolism in fed and fasted rats. Horm.Res.
4: 357-366, 1973.
- Herrera, E. and A. Pascual. Effect of an amphetamine derivative
on rat adipose tissue lipolysis and glycerol utilization in
vitro. Biochem.Pharmacol. 22: 3131-3133, 1973.
- Herrera, E. Effect of albumin on glycerol metabolism in rat
adipose tissue. Rev.Esp.Fisiol. 29: 155-162, 1973.
- Alemany, M. and E. Herrera. Effects of suckling and food deprivation
on the activity of citrate enzymes in the liver of the rat. Horm.Metabol.Res.
6: 264-267, 1974.
- Aranda, A. and E. Herrera. The effect of food deprivation on
in vivo gluconeogenesis in the suckling rat. Horm.Metabol.Res.
6: 381-385, 1974.
- Aranda, A. and E. Herrera. Liver lipogenesis in vivo
in fed and food deprived suckling rats. Rev.Esp.Fisiol. 30: 31-36,
1974.
- Castro, M., M. D. García, and E. Herrera. Effect of
thyroidectomy on the in vitro utilization of glucose by
hypophysis and hypothalamus in the rat. Steroids Lipids Res. 5:
276-281, 1974.
- Herrera, E. and E. Montoya. Ayuno y diabetes en el estudio
de las interrelaciones hidratos de carbono y grasas. In Fac.Biologia,
ed. Miscellanea Alcobé. Barcelona, Universidad de Barcelona.
1974, 141-152.
- Herrera, E. Estudio del metabolismo intermediario en la diabetes
experimental. Jorn.Diabetol. 5: 19-37, 1974.
- Herrera, E. Relaciones metabólicas feto-madre. In Universidad
de Sevilla, ed. Obesidad-diabetes. Sevilla, Publicaciones Universidad
de Sevilla. 1974, 165-173.
- Montoya, E. and E. Herrera. Effects of streptozotocin on liver
composition and blood glucose, ketone bodies and insulin in the
fed and fast male rat. Horm.Res. 5: 29-38, 1974.
- Montoya, E. and E. Herrera. Urinary excretion of nitrogenous
compounds and ketones in streptozotocin treated rats. Rev.Esp.Fisiol.
30: 151-154, 1974.
- Montoya, E. and E. Herrera. Effect of thyroid status on glycerol
metabolism in adipose tissue of fasted male rats. Horm.Res. 5:
129-140, 1974.
- Alemany, M. and E. Herrera. Lactate dehydrogenase and pyruvate
kinase levels in the liver of fed and 24 h fasted suckling rats.
Horm.Metabol.Res. 7: 523-524, 1975.
- Domínguez, M. C. and E. Herrera. Effect of epinephrine
on the synthesis of glyceride glycerol and adipose tissue in
vitro. Rev.Esp.Fisiol. 31: 293-298, 1975.
- Herrera, E. Effects of epinephrine and glucose on the in
vitro response of adipose tissue to sulfonylureas. Acta Diabetol.Lat.
12: 106-113, 1975.
- Herrera, E. Bioquímica general de glicéridos neutros,
ácidos grasos, fosfolípidos y cuerpos cetónicos.
In: Yañez, M. A. and F. C. Soriguer, eds. Dislipidemias,
lipidosis, lipodistrofias y obesidad. Sevilla, Publicaciones Universidad
de Sevilla. 1975, 29-89.
- Herrera, E. and N. Freinkel. Metabolites in the liver, brain
and placenta of fed or fasted mothers and fetal rats. Horm.Metabol.Res.
7: 247-249, 1975.
- Herrera, E. Effects of sulfonylureas (Tolbutamide, Glipentide
and Glibenclanide) on in vitro glycerol metabolism in adipose
tissue from rats. Life Sciences 16: 645-650, 1975.
- Herrera, E., R. Sandler, and N. Freinkel. Comparative changes
in liver composition, acetyl-CoA, and citric acid during fasting
in genetically obese hyperglycemic mice (ob/ob) and lean littermates.
Horm.Metabol.Res. 7: 70-74, 1975.
- Arola, L., A. Palou, E. Herrera, and M. Alemany. Determination
of plasma amino acids in small samples with the use of Dansyl-chloride.
Biochimie 58: 1221-1226, 1976.
- Domínguez, M. C. and E. Herrera. Effects of 2-deoxy-D-glucose,
oligomycin and theophylline on in vitro glycerol metabolism
in rat adipose tissue: response to insulin and epinephrine. Horm.Metabol.Res.
8: 33-37, 1976.
- Domínguez, M. C. and E. Herrera. Effects of glycerol
and glucose on the kinetics of glycerol utilization by adipose
tissue in the rat. Rev.Esp.Fisiol. 32: 293-300, 1976.
- Domínguez, M. C. and E. Herrera. The effect of glucose,
insulin and adrenaline on glycerol metabolism "in vitro"
in rat adipose tissue. Biochem.J. 158: 183-190, 1976.
- Herrera, E., M. Castro, and M. C. García. Mecanismos
de bociogénesis experimental. Anal.Univ.Hispalense 28:
131-144, 1976.
- Herrera, E. Efectos de las sulfonilureas sobre el metabolismo
del glicerol en tejido adiposo "in vitro". In
García Valdecasas, F. and E. Rodríguez Farré,
eds. Avances en Farmacología. Barcelona, Ed. Acacia. 1976,
421-424.
- Herrera, E. Aspectos moleculares de la transcripción
genética en la síntesis de proteínas. Oncología
80: 193-198, 1976.
- Arola, L., E. Herrera, and M. Alemany. A new method for deproteinization
of small samples of blood plasma for amino acid determination.
Anal.Biochem. 82: 236-239, 1977.
- Arola, Ll., A. Palou, E. Herrera, and M. Alemany. Nivells d'aminoacids
plasmatics en rates gestants i en llurs fetus. Butl.Soc.Catal.Ped.
37: 193-203, 1977.
- García-Rafanell, J., M. A. Lasunción, J. Morell,
and E. Herrera. Comparative hypoglycemic and hypoketonemic effects
of tolbutamide and glypentide in the rat. Rev.Esp.Fisiol. 33:
103-108, 1977.
- Herrera, E. Interrelaciones hidratos de carbono y grasas en
diabetes experimental y efecto de agentes hipoglucemiantes. Annals
de Medic. LXIII: 1474-1486, 1977.
- Herrera, E. and M. C. Domínguez. Modulación del
metabolismo del glicerol en tejido adiposo. In Cornudella, L.,
J. Oró, A. Sols, and C. Fernández de Heredia, eds.
Avances de la Bioquímica. Barcelona, Ed. Salvat. 1977,
237-244.
- Herrera, E. Metabolismo de los glicéridos en el tejido
adiposo. Investigación y Ciencia 4: 28-37, 1977.
- Martínez, J. M., M. Llobera, M. Cornella, and E. Herrera.
Effects of hypo and hyperthyroidism on the response to glucose
loading of blood glucose ketones and insulin and liver glycogen
as studied in the fasted rat. Rev.Esp.Fisiol. 33: 323-330, 1977.
- Alemany, M., A. Palou, J. Codina, and E. Herrera. Changes in
plasma amino acids levels and in vivo gluconeogenesis from
alanine in rats chronically treated with sulfonylureas. Diabete
Metab. 4: 181-186, 1978.
- Arola, Ll., A. Palou, X. Remesar, E. Herrera, and M. Alemany.
Different expressions for enzyme activities in organs of rat.
Application to aspartate transaminasa, glutamate dehydrogenase
and AMP-deaminase. Rev.Esp.Fisiol. 34: 345-350, 1978.
- Bellido, J. and E. Herrera. Utilization of pyruvate, alanine
and glutamate by isolated fat cells and their effects on glycerol
metabolism. Rev.Esp.Fisiol. 34: 429-436, 1978.
- Bellido, J. and E. Herrera. Effects of glucose on the metabolization
of fructose and glycerol by isolated adipocytes from rat. Rev.Esp.Fisiol.
34: 437-442, 1978.
- Chaves, J. M. and E. Herrera. In vitro glycerol metabolism
in adipose tissue from fasted pregnant rats. Biochem.Biophys.Res.Commun.
85: 1299-1306, 1978.
- Codina, J., M. A. Lasunción, and E. Herrera. Effects
of chronic and acute treatment with sulfonylureas on plasma insulin
and glucose levels in the rat. Diabete Metab. 4: 47-52, 1978.
- Herrera, E., J. M. Chaves, and A. Montes. Metabolismo lipídico
en el embarazo. C.N.Diab. 4: 55-61, 1978.
- Herrera, E. Interacciones metabólicas en el embarazo.
C.N.S.Cien.Fisiol. 17: 1-15, 1978.
- Herrera, E. Metabolismo intermediario durante el embarazo. Investigación
y Ciencia 19: 14-24, 1978.
- Lasunción, M. A. and E. Herrera. Thyroid function in
diabetic rats by the administration of streptozotocin. Endocrinología
25: 13-18, 1978.
- Llobera, M., M. J. Seibel, and E. Herrera. Metabolic response
to short periods of starvation in hypo and hyperthyroid rats.
Horm.Metabol.Res. 10: 319-324, 1978.
- Palou, A., M. Alemany, and E. Herrera. Effect of sulfonylurea
treatment and fasting on the levels of plasma aminoacids in the
rat. Horm.Metabol.Res. 10: 482-489, 1978.
- Remesar, X., E. Herrera, and M. Alemany. Glycogen phosphorylase
activities in sulfonylureas treated rats. Horm.Metabol.Res. 10:
355-356, 1978.
- Seibel, M. J., M. Llobera, and E. Herrera. Effects of glucose,
insulin and adrenalin on glycerol metabolism in adipose tissue
from hypothyroid rats. Mol.Cell.Endocrinol. 10: 307-318, 1978.
- Arola, L., E. Herrera, and M. Alemany. A method for the estimation
of striated muscle mass in small laboratory animals. Rev.Esp.Fisiol.
35: 215-218, 1979.
- Carmaniu, S. and E. Herrera. Conversion of (U-14C)-glycerol,
(2-3H)-glyecrol and (1-14C)-palmitate
into circulating lipoproteins in the rat. Rev.Esp.Fisiol. 35:
461-466, 1979.
- Carmaniu, S. and E. Herrera. Effect of evisceration on the
disposal of (14C)-palmitate
in the rat. Arch.Int.Physiol.Biochim. 87: 955-961, 1979.
- Codina, J. and E. Herrera. Effect of fasting on urinary excretion
of water and nitrogen in the rat. Rev.Esp.Fisiol. 35: 457-460,
1979.
- Cornellá, M., J. Codina, and E. Herrera. Effect of fasting
on circulating glucose, ketone bodies and insulin levels in the
suckling rat. Rev.Esp.Fisiol. 35: 347-352, 1979.
- Llobera, M., A. Montes, and E. Herrera. Lipoprotein lipase
activity in liver of the rat fetus. Biochem.Biophys.Res.Commun.
91: 272-277, 1979.
- Llobera, M., A. Muniesa, and E. Herrera. Effects of hypo- and
hyper-thyroidism on in vivo lipogenesis in fed and fasted
rats. Horm.Metabol.Res. 11: 628-634, 1979.
- Muniesa, A., M. Llobera, and E. Herrera. Adipose tissue cellularity
in hypo- and hyperthyroid rats. Horm.Res. 11: 254-261, 1979.
- Salas, P., M. Llobera, and E. Herrera. Growth and pituitary
content of growth hormone and prolactin in hypo and hyperthyroid
rats. Endocrinología 26: 152-158, 1979.
- Argilés, J. M. and E. Herrera. Effecte de l'insulina
sobre l'utilizació de lipoproteines de molt baixa densitat
(VLDL) per teixits extra-hepatics a la rata in vivo. Annals
de Medic. LXVI: 1007-1013, 1980.
- Arola, Ll., A. Palou, X. Remesar, E. Herrera, and M. Alemany.
Effect of stress and sampling site on metabolite concentration
in rat plasma. Arch.Int.Physiol.Biochim. 88: 99-105, 1980.
- Carmaniu, S. and E. Herrera. Extra-hepatic utilization of 14C-glucose
and 14C-glycerol in the eviscerated rat. Diabete Metab. 6: 239-244,
1980.
- Carmaniu, S. and E. Herrera. Comparative utilization in
vivo of (U-14C) glycerol,
(2-3H) glycerol, (U-14C)
glucose and (1-14C) palmitate
in the rat. Arch.Int.Physiol.Biochim. 88: 255-263, 1980.
- Carrillo, M., S. Zanuy, and E. Herrera. Daily rhythms of amino
acid levels in the plasma of golfish (Carassius Auratus). Comp.Biochem.Physiol.
67: 581-586, 1980.
- Chaves, J. M. and E. Herrera. In vivo glycerol metabolism
in the pregnant rat. Biol.Neonate 37: 172-179, 1980.
- Chaves, J. M. and E. Herrera. In vitro response of glycerol
metabolism to insulin and adrenalin in adipose tissue from fed
and fasted rats during pregnancy. Biol.Neonate 38: 139-145, 1980.
- Codina, J., M. Vall, and E. Herrera. Changes in plasma glucose,
insulin and glucagon levels, glucose tolerance tests and insulin
sensitivity with age in the rat. Diabete Metab. 6: 135-139, 1980.
- Herrera, E., B. Bonet, and R. Iglesias. Metabolic response
to starvation in the hypothyroid pregnant rat. Biochem.Soc.Transact.
8: 538-539, 1980.
- Herrera, E. Situación actual del conocimiento sobre
el mecanismo de acción de la insulina. Annals de Medic.
LXVI: 993-1001, 1980.
- Lasunción, M. A. and E. Herrera. Effect of heparin on
the utilization in vitro of labelled glycerides from triglyceride-rich
lipoproteins in rat adipose tissues. Arch.Int.Physiol.Biochim.
88: 385-391, 1980.
- Lasunción, M. A. and E. Herrera. Incubation of labelled
triglyceride-rich lipoproteins with rat adipose tissue in the
presence of heparin. Biochem.Soc.Transact. 8: 539-540, 1980.
- Lasunción, M. A. and E. Herrera. Effect of rat serum
on glycerol metabolism in adipose tissue in vitro. Arch.Int.Physiol.Biochim.
88: 437-441, 1980.
- Llobera, M. and E. Herrera. Effects of starvation on in
vivo gluconeogenesis in hypo and hyperthyroid rats. Endocrinology
106: 1628-1633, 1980.
- Mampel, T. and E. Herrera. Efectes comparatius de la insulina
sobre el metabolisme de la glucosa i el glicerol en teixits extrahepatics.
Annals de Medic. 66: 1148-1153, 1980.
- Mena, M. A. and E. Herrera. Monoamine metabolism in rat brain
regions following long term alcohol tratment. J.Neural.Transm.
47: 227-236, 1980.
- Soley, M., M. Llobera, R. Chieri, and E. Herrera. Efecte de
la insulina sobre el metabolisme hidrocarbonat al fetge. Annals
de Medic. LXVI: 1014-1021, 1980.
- Testar, X., M. A. Lasunción, R. Chieri, and E. Herrera.
Aproximació a l'estudi del transport placentari de glucosa:
efecte de la insulina. Annals de Medic. LXVI: 1022-1030, 1980.
- Argilés, J. and E. Herrera. Lipids and lipoproteins in
maternal and fetus plasma in the rat. Biol.Neonate. 39: 37-44,
1981.
- Argilés, J. and E. Herrera. Changes in lipid composition
of plasma lipoproteina after total hepatectomy in the rat. Arch.Int.Physiol.Biochim.
89: 461-465, 1981.
- Arola, Ll., A. Palou, X. Remesar, E. Herrera, and M. Alemany.
Effect of ether, sodium pentobarbital and chloral hydrate anesthesia
on rat plasma metabolite concentrations. Rev.Esp.Fisiol. 37: 379-386,
1981.
- Carmaniu, S. and E. Herrera. Efecte de la insulina en el metabolisme
del glicerol in vivo en la rata. Bul.Soc.Catal.Biol. 5-6:
145-151, 1981.
- Chaves, J. M. and E. Herrera. Efecto de la insulina y el ayuno
sobre el metabolismo in vitro del glicerol por el tejido
adiposo de la rata preñada. Bul.Soc.Catal.Biol. 5-6: 137-144,
1981.
- Codina, J. and E. Herrera. Variacions de les relacions glucosa/insulina
pel tractament amb sulfonilurees en la rata. Bul.Soc.Catal.Biol.
5-6: 163-169, 1981.
- Fando, J. J. L., F. Domínguez, and E. Herrera. Tryptophan
overload in the pregnant rat: effect on brain amino acid levels
and in vitro protein synthesis. J.Neurochem. 37: 324-329,
1981.
- Herrera, E. and M. A. Lasunción. Adaptación metabólica
en el embarazo. In Hernández, M., ed. Nutrición,
crecimiento y desarrollo. Bilbao, Fund. Orbegozo. 1981, 122-131.
- Herrera, E. Regulación del metabolismo del tejido adiposo.
Annals de Medic. LXVII: 415-427, 1981.
- Herrera, E. and M. Llobera. Ethanol toxicity: lipid and carbohydrate
metabolism; ethanol in pregnancy and the fetal alcohol syndrome.
In Brown, S. S. and D. S. Davies, eds. Organ-directed toxicity
chemical indixes and mechanisms. Oxford, Pergamon Press. 1981,
11-23.
- Lasunción, M. A. and E. Herrera. Effect of pregnancy
on the uptake of lipoprotein triglyceride fatty acids by isolated
adipocytes in the rat. Biochem.Biophys.Res.Commun. 98: 227-233,
1981.
- Lasunción, M. A. and E. Herrera. "In vitro"
utilization of labelled esterified fatty acids and glyceride glycerol
from triglyceride-rich lipoproteins in rat adipose tissue. Horm.Metabol.Res.
13: 335-339, 1981.
- Lasunción, M. A., M. Llobera, and E. Herrera. Morphological
and compositional changes of rat plasma triglyceride-rich lipoproteins
incubated with adipose tissue. Arch.Int.Physiol.Biochim. 89: 57-62,
1981.
- Lasunción, M. A. and E. Herrera. Alteraciones de la
actividad tiroidea en la diabetes experimental. Bul.Soc.Catal.Biol.
5-6: 87-94, 1981.
- Llobera, M. and E. Herrera. Metabolisme intermediari en l'hipo
i hipertiroidisme experimental: effectes de temps curts de dejuni.
Bul.Soc.Catal.Biol. 5-6: 95-113, 1981.
- Mampel, T., R. Camprodon, J. Solsona, V. Junca, and E. Herrera.
Changes in circulating glycerol, free fatty acids and glucose
levels following liver transplant in the pig. Arch.Int.Physiol.Biochim.
89: 195-199, 1981.
- Martín del Río, R., R. Camprodón, J. M.
Fabregat, J. M. Ramón, and E. Herrera. Plasma levels of
amino acids in human, pigs and rats and their changes during liver
transplantation in the pig. Comp.Biochem.Physiol.[A] 70: 309-313,
1981.
- Palou, A., X. Remesar, Ll. Arola, E. Herrera, and M. Alemany.
Metabolic effects of short term food deprivation in the rat. Horm.Metabol.Res.
13: 326-330, 1981.
- Palou, A., M. Alemany, and E. Herrera. Estudi comparatiu de
l'aminograma plasmatic en rates tractades a temps curts i prolongats
AMB sulfonilurees. Bul.Soc.Catal.Biol. 5-6: 171-181, 1981.
- Remesar, X., Ll. Arola, A. Palou, E. Herrera, and M. Alemany.
Valor del l'aminograma plasmatic en rates hipotiroidees i hipertiroidees.
Bul.Soc.Catal.Biol. 5-6: 115-124, 1981.
- Remesar, X., L. Arola, A. Palou, E. Herrera, and M. Alemany.
Plasma amino acids in hypothyroid and hyperthyroid rats. Horm.Metabol.Res.
13: 38-41, 1981.
- Carrillo, M., S. Zanuy, and E. Herrera. Growth and diurnal
variations in metabolic parameters in the starved bass, Dicentrarchus
Labrax, after experimental feeding. Comp.Biochem.Physiol.[A] 72:
11-16, 1982.
- Codina, J., B. Vall, and E. Herrera. Comparative changes with
age of the fasting response in circulatin ketones bodies, glucose
and insulin and oral glucose tolerance test in the rat. Comp.Biochem.Physiol.[A]
71: 231-236, 1982.
- Codina, J. and E. Herrera. Effect of fasting on the circulating
glucose and insulin levels after glucose, arginine, pyruvate and
palmitate administration in the rat. Molecular Physiol. 3: 193-201,
1982.
- Herrera, E. and A. Zorzano. Effects of nembutal and ether anaesthesia
on gluconeogenesis "in vivo" in the rat. Biochem.Soc.Trans.
10: 394-395, 1982.
- Herrera, E. Alteracions metaboliques en l'hipotiroidisme. Traballs
Soc.Cat.Biol. 34: 3-16, 1982.
- Jolín, T. and E. Herrera. Effects of strectozotocin-diabetes
and L-thyroxine treatment on plasma amino acid levels in thyroidectomized
rats. Horm.Metabol.Res. 14: 398-404, 1982.
- Mena, M. A., M. Salinas, R. Martín del Río, and
E. Herrera. Effects of maternal ethanol ingestion on cerebral
neurotransmitters and cyclic -AMP in the rat offspring. Gen.Pharmacol.
13: 241-248, 1982.
- Palacín, M. and E. Herrera. Biological potencies of
different insulins in isolated adipocytes. Biochem.Soc.Trans.
10: 395, 1982.
- Salinas, M., A. Galán, and E. Herrera. Fetal and early
postnatal development of adenylate cyclase and cyclic AMP phosphodiesterase
activities in rat brain. Biol.Neonate 41: 94-100, 1982.
- Soley, M., E. Herrera, and M. Alemany. Effect of a 24 h fast
on the amino acid concentrations of rat blood, liver and striated
muscle. Molecular Physiol. 2: 89-98, 1982.
- Argiles, J. and E. Herrera. Effects of insulin on the disposal
of 14C-labelled very low density lipoprotein triglycerides in
intact and hepatectomized rats. Diabetologia 24: 300-303, 1983.
- Fragoso, J., M. Palacín, A. Zorzano, B. Bonet, M. A.
Lasunción, M. Durfort, M. Díaz, and E. Herrera.
Tratamiento crónico con anilidas en un estudio experimental
sobre la etiología del síndrome tóxico. In
C.S.I.C., ed. Programa del CSIC para el estudio del síndrome
tóxico. Madrid, Consejo Superior de Investigaciones Científicas.
1983, 117-136.
- Herrera, E., A. Zorzano, and V. Fresneda. Comparative kinetics
of human and rat liver alcohol dehydrogenase. Biochem.Soc.Trans.
11: 729-730, 1983.
- Herrera, E. and A. Zorzano. Efecto del alcohol en la gestación:
síndrome del alcoholismo fetal. Rev.Esp.Pediat. 39: 301-310,
1983.
- Jolin, T., C. Gonzalez, and E. Herrera. Effects of streptozotocin-diabetes
and L-thyroxine treatment on TSH and GH, and circulating glucose
and glycerol in thyroidectomized rats. Comp.Biochem.Physiol. 76:
265-269, 1983.
- Lasunción, M. A., M. Palacín, and E. Herrera.
Method for the infusion of periuterine adipose tissue in situ
in the rat. Biochem.Soc.Trans. 11: 732-734, 1983.
- Lasunción, M. A. and E. Herrera. Changes with starvation
in the rat of the lipoprotein lipase activity and hydrolysis of
triacylglycerols from triacylglycerol- rich lipoproteins in adipose
tissue preparations. Biochem.J. 210: 639-643, 1983.
- Lasunción, M. A., X. Testar, M. Palacín, R. Chieri,
and E. Herrera. Method for the study of metabolite transfer from
rat mother to fetus. Biol.Neonate. 44: 85-92, 1983.
- Lasunción, M. A., C. Gonzalez, T. Jolin, and E. Herrera.
Effects of streptozotocin diabetes and insulin treatment on adipose
tissue glucose utilization in the rat. Arch.Int.Physiol.Biochim.
91: 247-254, 1983.
- Ludeña, M. C., M. A. Mena, M. Salinas, and E. Herrera.
Effects of alcohol ingestion in the pregnant rat on daily food
intake, offspring growth and metabolic parameters. Gen.Pharmacol.
14: 327-332, 1983.
- Mitjavila, M. T., J. Codina, C. Stampa, and E. Herrera. Modificación
del tránsito digestivo por un analgésico anti-inflamatorio
(isonixina) y su restablecimiento por la metoclopramida. Arch.Farmacol.Toxicol.
9: 125-130, 1983.
- Palacín, M., M. A. Lasunción, and E. Herrera.
Transfer from mother to foetus of L-alanine and glycerol in fed
and 48h-starved pregnant rats. Biochem.Soc.Trans. 11: 731-732,
1983.
- Ramirez, I., M. Llobera, and E. Herrera. Circulating triacylglycerols,
lipoproteins, and tissue lipoprotein lipase activities in rat
mothers and offspring during the perinatal period: effect of postmaturity.
Metabolism 32: 333-341, 1983.
- Ramirez, J. I., M. Llobera, and E. Herrera. Method for triglyceride
measurement in small amounts of plasma. Rev.Esp.Fisiol. 39: 327-331,
1983.
- Soley, M., R. Chieri, and E. Herrera. Liver glucose, glycogen
and lipid synthesis in fed and 24-hour fasted rats soon after
a pulse of [3-14C]pyruvate through the portal vein. Int.J.Biochem.
15: 45-49, 1983.
- Zorzano, A. and E. Herrera. Liver glycogen and glyceride glycerol
formation as compared with glucose synthesis in 24h-starved virgin
and pregnant rats. Biochem.Soc.Trans. 11: 730-731, 1983.
- Herrera, E. and A. Zorzano. Is the rat a proper model for studying
the diabetogenic tendencies in pregnancy? In Shafrir, E. and A.
E. Renold, eds. Lessons from animal diabetes. London, Libby Co.
1984, 699-704.
- Herrera, E., D. Lopez, X. Testar, A. Zorzano, and M. Llobera.
Efectos del consumo materno de alcohol durante la gestación.
Estudio experimental. In Fundación Valgrande, ed. Síndrome
alcohólico fetal. Madrid, Egraf,S.A. 1984, 213-226.
- Mena, M. A., R. Martin del Rio, and E. Herrera. The effect
of long-term ethanol maternal ingestion and withdrawal on brain
regional monoamine and amino acid precursors in 15-day-old rats.
Gen.Pharmacol. 15: 151-154, 1984.
- Palacín, M., M. A. Lasunción, and E. Herrera.
Transporte de metabolitos a través de la placenta. Rev.Esp.Pediat.
40: 163-198, 1984.
- Zorzano, A. and E. Herrera. Liver and kidney cortex gluconeogenesis
from L-alanine in fed and starved rats. Int.J.Biochem. 16: 263-267,
1984.
- Zorzano, A. and E. Herrera. Effects of anesthetics and starvation
on in vivo gluconeogenesis in virgin and pregnant rats.
Metabolism 33: 553-558, 1984.
- Fando, J. L., T. Jolin, M. Salinas, F. Dominguez, and E. Herrera.
The effect of streptozotocin diabetes on brain protein synthesis
in the rat. Diabete.Metab. 11: 92-97, 1985.
- Gómez-Coronado, D., M. Soley, and E. Herrera. Insulin
effect on "in vivo" gluconeogenesis from (3-14C)-pyruvate
in the starved rat. Int.J.Biochem. 17: 1307-1311, 1985.
- Grinberg, D. R., I. Ramirez, S. Vilaró, M. Reina, M.
Llobera, and E. Herrera. Starvation enhances lipoprotein lipase
activity in the liver of the newborn rat. Biochim.Biophys.Acta
833: 217-222, 1985.
- Herrera, E., M. Palacín, A. Martín, and M. A.
Lasunción. Relationship between maternal and fetal fuels
and placental glucose transfer in rats with maternal diabetes
of varying severity. Diabetes 34(Suppl.2): 42-46, 1985.
- Mampel, T. and E. Herrera. Effects of insulin on the utilization
of 14C-glycerol and 14C-glucose in hepatectomized nephrectomized
rats. Diabete.Metab. 11: 118-124, 1985.
- Mampel, T., F. Villarroya, and E. Herrera. Hepatectomy-nephrectomy
effects in the pregnant rat and fetus. Biochem.Biophys.Res.Commun.
131: 1219-1225, 1985.
- Palacín, M., M. A. Lasunción, and E. Herrera.
Placental permeability to metabolites in fed and starved rats.
Biochem.Soc.Transact. 13: 198-199, 1985.
- Palacín, M., M. A. Lasunción, R. M. del Rio,
and E. Herrera. Placental formation of lactate from transferred
L-alanine and its impairment by aminooxyacetate in the late-pregnant
rat. Biochim.Biophys.Acta 841: 90-96, 1985.
- Palacín, M., M. A. Lasunción, A. Martín,
and E. Herrera. Decreased uterine blood flow in the diabetic pregnant
rat does not modify the augmented glucose transfer to the fetus.
Biol.Neonate. 48: 197-203, 1985.
- Soley, M., R. Chieri, and E. Herrera. Short-term insulin infused
through the portal vein enhances liver gluconeogenesis and glycogenesis
from [3-14C]pyruvate in the starved rat. Int.J.Biochem. 17: 689-693,
1985.
- Soley, M., R. Chieri, M. Llobera, and E. Herrera. Glucose infused
through the portal vein enhances liver gluconeogenesis and glycogenesis
from [3-14C]pyruvate in the starved rat. Int.J.Biochem. 17: 685-688,
1985.
- Testar, X., M. A. Lasunción, R. Chieri, and E. Herrera.
Effects of exogenous insulin on placental transfer of maternal
glucose to the rat fetus. Diabetologia 28: 743-748, 1985.
- Testar, X., M. Llobera, and E. Herrera. Increase with starvation
in the pregnant rat of the liver lipoprotein lipase. Biochem.Soc.Trans.
13: 134, 1985.
- Villarroya, F., T. Mampel, and E. Herrera. Similar metabolic
response to acute ethanol intake in pregnant and non-pregnant
rats either fed or fasted. Gen.Pharmacol. 16: 537-540, 1985.
- Herrera, E. Adaptaciones metabólicas en la madre durante
la gestación. In Herrera, E., ed. Bioquímica Perinatal.
Madrid, Fundación Ramón Areces. 1986, 9-28.
- Herrera, E. Efectos del etanol en la gestación. Mundo
Científico 6: 1114-1119, 1986.
- Herrera, E. and M. A. Lasunción. Metabolismo de las
lipoproteínas de muy baja densidad. In Ochoa, S., L. F.
Leloir, and J. Oró, eds. Bioquímica y Biología
Molecular. Barcelona, Salvat Editores. 1986, 166-172.
- Herrera, E., A. Martín, M. Palacín, and M. A.
Lasunción. Placental modification of transferred maternal
substrates in normal and diabetic rats. In Serrano Ríos,
M. and P. J. Lefebvre, eds. Diabetes-1985. Amsterdam, Excerpta
Medica. 1986, 570-574.
- López Tejero, D., I. Ferrer, M. Llobera, and E. Herrera.
Effects of prenatal ethanol exposure on physical growth, sensory
reflex maturation and brain development in the rat. Neuropathol.Appl.Neurobiol.
12: 251-260, 1986.
- López-Luna, P., T. Muñoz, and E. Herrera. Body
fat in pregnant rats at mid- and late-gestation. Life Sci. 39:
1389-1393, 1986.
- Martín, A., A. Zorzano, I. Caruncho, and E. Herrera.
Glucose tolerance tests and "in vivo" response
to intravenous insulin in the unanaesthesized late pregnant rat
and theirconsequences to the fetus. Diabete.Metab. 12: 302-307,
1986.
- Mena, M. A., A. Zorzano, and E. Herrera. Acute effects of ethanol
on brain, plasma and adrenal monoamine concentrations in virgin
and pregnant rats and their fetuses. Neurochem.Int. 9: 371-378,
1986.
- Testar, X., D. Lopez, M. Llobera, and E. Herrera. Ethanol administration
in the drinking fluid to pregnant rats as a model for the fetal
alcohol syndrome. Pharmacol.Biochem.Behav. 24: 625-630, 1986.
- Vinas, O., S. Vilaró, X. Remesar, and E. Herrera. Effects
of chronic ethanol ingestion on circulating metabolites and liver
composition in the lactating rat. Gen.Pharmacol. 17: 197-202,
1986.
- Zorzano, A., M. A. Lasunción, and E. Herrera. Role of
the availability of substrates on hepatic and renal gluconeogenesis
in the fasted late pregnant rat. Metabolism 35: 297-303, 1986.
- Zorzano, A. and E. Herrera. Comparative utilization of glycerol
and alanine as liver gluconeogenic substrates in the fed late
pregnant rat. Int.J.Biochem. 18: 583-587, 1986.
- Herrera, E., D. Gomez Coronado, and M. A. Lasunción.
Lipid metabolism in pregnancy. Biol.Neonate. 51: 70-77, 1987.
- Herrera, E. Metabolismo general de aminoácidos. In Aula
Médica, ed. Sustrato protéico. Madrid, Ediciones
CEA,S.A. 1987, 7-20.
- Herrera, E., M. A. Lasunción, D. Gómez-Coronado,
and E. Orozco. Papel de la lipoproteína lipasa de la pared
vascular en el metabolismo de las lipoproteínas ricas en
triglicéridos. Actas III Reun.Latin.Invest.Vascular 15-26,
1987.
- Lasunción, M. A., J. Lorenzo, M. Palacín, and
E. Herrera. Maternal factors modulating nutrient transfer to fetus.
Biol.Neonate. 51: 86-93, 1987.
- Palacín, M., M. A. Lasunción, and E. Herrera.
Lactate production and absence of gluconeogenesis from placental
transferred substrates in fetuses from fed and 48-H starved rats.
Pediatr.Res. 22: 6-10, 1987.
- Vilaró, S., O. Vinas, X. Remesar, and E. Herrera. Effects
of chronic ethanol consumption on lactational performance in rat:
mammary gland and milk composition and pups' growth and metabolism.
Pharmacol.Biochem.Behav. 27: 333-339, 1987.
- Vilaró, S., O. Vinas, E. Herrera, and X. Remesar. Chronic
and acute ethanol impair the in vivo glucose uptake by
lactating rat mammary gland. Biosci.Rep. 7: 777-781, 1987.
- Vinas, O., S. Vilaró, E. Herrera, and X. Remesar. Effects
of chronic ethanol treatment on amino acid uptake and enzyme activities
in the lactating rat mammary gland. Life Sci. 40: 1745-1749, 1987.
- Bonet, B. and E. Herrera. Different response to maternal hypothyroidism
during the first and second half of gestation in the rat. Endocrinology
122: 450-455, 1988.
- Herrera, E. and M. A. Lasunción. Metabolismo de las
lipoproteínas ricas en triglicéridos. In Aula Médica,
ed. Substrato lipídico. Madrid, Ediciones CEA,S.A. 1988,
89-99.
- Herrera, E., X. Testar, M. Llobera, and A. Zorzano. Efectos
metabólicos del etanol. Alcohol en la gestación
y sus consecuencias en las relaciones feto/madre. In Herrera,
E., ed. Bioquímica Perinatal: Aspectos básicos y
patológicos. Madrid, Fundación Ramón Areces,
Ed. Ceura. 1988, 577-600.
- Herrera, E., M. A. Lasunción, D. Gomez Coronado, P. Aranda,
P. Lopez Luna, and I. Maier. Role of lipoprotein lipase activity
on lipoprotein metabolism and the fate of circulating triglycerides
in pregnancy. Am.J.Obstet.Gynecol. 158: 1575-1583, 1988.
- Herrera, E. Aspectos básicos de las adaptaciones metabólicas
en la madre durante la gestación y relaciones materno-fetales.
In Herrera, E., ed. Bioquímica Perinatal: Aspectos básicos
y patológicos. Madrid, Fundación Ramón Areces,
Ed. Ceura. 1988, 17-40.
- Herrera, E., M. A. Lasunción, D. Gómez-Coronado,
and E. Orozco. Papel de la lipoproteína lipasa en el metabolismo
de las lipoproteínas, con especial referencia a las VLDL.
Drugs of Today 24 (supl. 1): 65-72, 1988.
- Herrera, E., M. A. Lasunción, M. Castro, D. Gomez Coronado,
A. Martín, and G. Quack. Studies with etofibrate in the
rat. Part I: Effects on glycerol, free fatty acid and triacylglycerol
metabolism. Biochim.Biophys.Acta 963: 42-52, 1988.
- Lasunción, M. A. and E. Herrera. Metabolismo de las
lipoproteínas transportadoras del colesterol. In Aula Médica,
ed. Substrato lipídico. Madrid, Ediciones CEA,S.A. 1988,
101-112.
- Lopez Tejero, D., M. Llobera, and E. Herrera. High liver lipoprotein
lipase activity in hyperlipemic developing rats from undernourished
pregnant mothers. Biosci.Rep. 8: 309-314, 1988.
- Lopez Tejero, D., M. Llobera, and E. Herrera. Consecuencias
del alcohol durante la gestación sobre el desarrollo postnatal.
In Herrera, E., ed. Bioquímica Perinatal: Aspectos básicos
y patológicos. Madrid, Fundación Ramón Areces,
Ed. Ceura. 1988, 601-628.
- Palacín, M., M. A. Lasunción, and E. Herrera.
Utilization of glucose, alanine, lactate, and glycerol as lipogenic
substrates by periuterine adipose tissue in situ in fed and starved
rats. J.Lipid Res. 29: 26-32, 1988.
- Robert, M. Q. and E. Herrera. Effect of postweaning thyroid
status on endocrine and adipose development in rats. Am.J.Physiol.
255: E280-E286, 1988.
- Testar, X., M. Llobera, and E. Herrera. Metabolic response
to starvation at late gestation in chronically ethanol-treated
and pair-fed undernourished rats. Metabolism 37: 1008-1014, 1988.
- Testar, X., M. Llobera, and E. Herrera. Comparative metabolic
effects of chronic ethanol intake and undernutrition in pregnant
rats and their fetuses. Alcohol Clin.Exp.Res. 12: 197-200, 1988.
- Zorzano, A. and E. Herrera. Pregnancy and pentobarbital anaesthesia
modify hepatic synthesis of acylglycerol glycerol and glycogen
from gluconeogenic precursors during fasting in rats. Biochem.J.
256: 487-491, 1988.
- Argiles, J. and E. Herrera. Appearance of circulating and tissue
14C-lipids after oral 14C-tripalmitate administration in the
late pregnant rat. Metabolism 38: 104-108, 1989.
- Gómez-Coronado, D., M. A. Lasunción, and E. Herrera.
Lipoproteínas transportadoras de triglicéridos (I).
Clin.Invest.Arterioscl. 1: 30-44, 1989.
- Gómez-Coronado, D., M. A. Lasunción, and E. Herrera.
Lipoproteínas transportadoras de triglicéridos (II).
Clin.Invest.Arterioscl. 1: 116-129, 1989.
- Herrera, E. Las lipoproteínas; su papel en el riesgo
de las enfermedades cardiovasculares y su metabolismo. Rev.Fac.Med.UNAM
322: 59-68, 1989.
- Herrera, E., M. Castro, M. A. Lasunción, and A. Entrala.
Metabolismo de la vitamina A y su relación con las lipoproteínas
circulantes. Nutr.Clín. 9: 23-36, 1989.
- Lopez Tejero, D., M. Llobera, and E. Herrera. Permanent abnormal
response to a glucose load after prenatal ethanol exposure in
rats. Alcohol 6: 469-473, 1989.
- Lopez Tejero, D., E. Arilla, B. Colas, M. Llobera, and E. Herrera.
Low intestinal lactase activity in offspring from ethanol- treated
mothers. Biol.Neonate. 55: 204-213, 1989.
- Zorzano, A. and E. Herrera. Decreased in vivo rate of
ethanol metabolism in the suckling rat. Alcohol Clin.Exp.Res.
13: 527-532, 1989.
- Zorzano, A., L. Ruiz del Arbol, and E. Herrera. Effect of liver
disorders on ethanol elimination and alcohol and aldehyde dehydrogenase
activities in liver and erythrocytes.Clin.Sci. 76: 51-57, 1989.
- Zorzano, A. and E. Herrera. Disposition of ethanol and acetaldehyde
in late pregnant rats and their fetuses. Pediatr.Res. 25: 102-106,
1989.
- Zorzano, A., M. Soley, and E. Herrera. Rapid effects of insulin
and glucose on the hepatic incorporation of gluconeogenic substrates
into glyceride glycerol and glycogen. Int.J.Biochem. 21: 1071-1075,
1989.
- Alvarez, J. J., M. A. Lasunción, J. M. Olmos, and E.
Herrera. Interferencia de la lipoproteína (a) en la cuantificación
del colesterol de las HDL mediante ultracentrifugación.
Clin.Invest.Arterioscl. 2: 146-152, 1990.
- Arilla, E., V. Barrios, A. Martín, and E. Herrera. Somatostatin
concentration in gastric and colonic mucosa of normal and streptozotocin-diabetic
pregnant rats. Endocrinología 37: 45-48, 1990.
- Entrala, A., M. A. Lasunción, J. M. Olmos, E. Herrera,
and A. Sastre. Ingesta dietética y otros factores de riesgo
cardiovascular en el personal laboral-sanitario del Hospital Ramón
y Cajal. Nutr.Clín. 10: 7-26, 1990.
- Herrera, E., P. Ramos, and A. Martín. Control by insulin
of adipose tissue lipoprotein lipase activity during late pregnancy
in the rat. In Shafrir, E., ed. Frontiers in Diabetes Research.
Lessons From Animal Diabetes III. London, Smith-Gordon. 1990,
551-554.
- Herrera, E. Las lipoproteínas: su papel en el riesgo
de las enfermedades cardiovasculares y metabolismo. In Pons, A.
and A. Palou, eds. Bioquímica y nutrición. Barcelona,
Fundación Caja de Pensiones. 1990, 11-30.
- Herrera, E. Contradiciones y realidades de los efectos de la
insulina sobre el metabolismo. Avanc.Diabet. 3: 3-19, 1990.
- Herrera, E., M. A. Lasunción, D. Gómez-Coronado,
A. Martín, and B. Bonet. Lipid metabolic interactions in
the mother during pregnancy and their fetal repercussions. In
Cuezva, J. M., A. M. Pascual Leone, and M. S. Patel, eds. Endocrine
and biochemical development of the fetus and neonate. New York,
Plenum Press. 1990, 213-230.
- Herrera, E. and M. A. Lasunción. Nutrición fetal.
Transporte placentario de metabolitos y adaptaciones metabólicas
de la madre. In Briones, J., J. Fons, V. Marco, C. Paredes, and
J. Morán, eds. Metabolismo, nutrición y alimentación
del prematuro y recién nacido de bajo peso. Madrid, Ene
Ediciones,S.A. 1990, 37-50.
- Herrera, E. Interrelaciones metabólicas materno-fetal
en la diabetes gestacional. Avanc.Diabet. 3: 51-56, 1990.
- Lasunción, M. A., A. Iglesias, N. Skottova, E. Orozco,
and E. Herrera. High-density lipoprotein subpopulations as substrates
for the transfer of cholesteryl esters to very-low-density lipoproteins.
Biochem.J. 270: 441-449, 1990.
- Martín, A., M. Palacín, M. A. Lasunción,
and E. Herrera. Fetal/maternal plasma amino acid relationships
in the streptozotocin diabetic rat. In Cuezva, J. M., A. M. Pascual
Leone, and M. S. Patel, eds. Endocrine and biochemical development
of the fetus and neonate. New York, Plenum Press. 1990, 277-282.
- Zorzano, A. and E. Herrera. In vivo ethanol elimination
in man, monkey and rat: a lack of relationship between the ethanol
metabolism and the hepatic activities of alcohol and aldehyde
dehydrogenases. Life Sci. 46: 223-230, 1990.
- Zorzano, A. and E. Herrera. Differences in kinetic characteristics
and in sensitivity to inhibitors between human and rat liver alcohol
dehydrogenase and aldehyde dehydrogenase. Gen.Pharmacol. 21: 697-702,
1990.
- Zorzano, A. and E. Herrera. Differences in the kinetic properties
and sensitivity to inhibitors of human placental, erythrocyte,
and major hepatic aldehyde dehydrogenase isoenzymes. Biochem.Pharmacol.
39: 873-878, 1990.
- Bonet, B. and E. Herrera. Maternal hypothyroidism during the
first half of gestation compromises normal catabolic adaptations
of late gestation in the rat. Endocrinology 129: 210-216, 1991.
- Herrera, E. and M. A. Lasunción. Metabolismo lipídico
en la madre durante la gestación y su repercusión
en el de la glándula mamaria. In Doménech.E., R.
Castro, C. Ormazábal, A. Méndez, and J. Morán,
eds. Alimentación del prematuro con leche humana. Necesidades
de su suplementación. Barcelona, Ediciones Científicas
y Técnicas,S.A. 1991, 63-73.
- Herrera, E., M. A. Lasunción, M. Palacín, A. Zorzano,
and B. Bonet. Intermediary metabolism in pregnancy. First theme
of the Freinkel era. Diabetes 40 Suppl 2: 83-88, 1991.
- Lopez Luna, P., I. Maier, and E. Herrera. Carcass and tissue
fat content in the pregnant rat. Biol.Neonate. 60: 29-38, 1991.
- Martín, A. and E. Herrera. Different responses to maternal
diabetes during the first and second half of gestation in the
streptozotocin-treated rat. Isr.J.Med.Sci. 27: 442-448, 1991.
- Palacín, M., M. A. Lasunción, M. Asunción,
and E. Herrera. Circulating metabolite utilization by periuterine
adipose tissue in situ in the pregnant rat. Metabolism 40: 534-539,
1991.
- Teruel, J. L., M. A. Lasunción, M. A. Castanon, N. Gallego,
E. Herrera, and J. Ortuno. Treatment of homozygotic familial hypercholesterolemia
with continuous apheresis of low density lipoproteins. Med.Clin.(Barc).
97: 738-740, 1991.
- Teruel, J. L., M. A. Lasunción, M. A. Castañón,
E. Herrera, and J. Ortuño. Aféresis de lipoproteínas
con columnas de sulfato de dextrano. Clin.Invest.Arterioscl. 3:
13-18, 1991.
- Alvarez, J. J., M. A. Lasunción, J. M. Olmos, and E.
Herrera. Studies on Lp(a) distribution in ultracentrifugally separated
lipoprotein fractions. Beckman Analytical s.p.a.Edition 35-43,
1992.
- Bocos, C., M. Castro, E. Orozco, J. A. Contreras, and E. Herrera.
A rapid and sensitive method for HPLC cholesterol determination
in bile. Rev.Esp.Fisiol. 48: 211-214, 1992.
- Contreras, J. A., M. Castro, C. Bocos, E. Herrera, and M. A.
Lasunción. Combination of an enzymatic method and HPLC
for the quantitation of cholesterol in cultured cells. J.Lipid
Res. 33: 931-936, 1992.
- Herrera, E., M. A. Lasunción, and M. Asunción.
Placental transport of free fatty acids, glycerol and ketone bodies.
In Polin, R. and W. W. Fox, eds. Fetal and neonatal physiology.
Philadelphia, W.B.Saunders. 1992, 291-298.
- Herrera, E., A. Martín, A. Montelongo, M. Domínguez,
and M. A. Lasunción. Serum lipid profile in diabetic pregnancy.
Avanc.Diabet. 5 (Supl. 1): 73-84, 1992.
- Herrera, E. and M. A. Lasunción. Adaptaciones metabólicas
en la madre durante la gestación y sus repercusiones en
la nutrición fetal. Actualidad Nutricional 12: 39-46, 1992.
- Herrera, E., M. A. Lasunción, A. Martín, and
A. Zorzano. Carbohydrate-lipid interactions in pregnancy. In Herrera,
E. and R. H. Knopp, eds. Perinatal biochemistry. Boca Raton, CRC
Press. 1992, 1-18.
- Knopp, R. H., B. Bonet, M. A. Lasunción, A. Montelongo,
and E. Herrera. Lipoprotein metabolism in pregnancy. In Herrera,
E. and R. H. Knopp, eds. Perinatal Biochemistry. Boca Raton, CRC
Press. 1992, 19-51.
- Lasunción, M. A., D. Gómez-Coronado, and E. Herrera.
Metabolismo de quilomicrones y VLDL. In Rubíes-Prat, J.,
ed. Temas actuales en hiperlipidemias y arteriosclerosis. Barcelona,
Espaxs, Publicaciones Médicas. 1992, 39-64.
- Lasunción, M. A. and E. Herrera. Métodos para
la determinación en plasma de actividades enzimáticas
relacionadas con el metabolismo lipídico. In Sociedad Española
de Arteriosclerosis, ed. Manual de las Clínicas de Lípidos
Españolas. Madrid, Jarpyo Editores,S.A. 1992, 49-53.
- Lasunción, M. A., J. L. Teruel, J. J. Alvarez, D. Gómez-Coronado,
J. Ortuño, and E. Herrera. Lipoproteína (a) en suero
durante el tratamiento con aféresis de LDL en la hipercolesterolemia
familiar homocigótica. Med.Clin.(Barc). 99: 541-544, 1992.
- Montelongo, A., M. A. Lasunción, L. F. Pallardo, and
E. Herrera. Longitudinal study of plasma lipoproteins and hormones
during pregnancy in normal and diabetic women. Diabetes 41: 1651-1659,
1992.
- Muñoz, C., P. López-Luna, and E. Herrera. Glucose
tolerance tests during gestation in the unanesthetized rat. Rev.Esp.Fisiol.
48: 97-102, 1992.
- Olmos, J. M., M. A. Lasunción, and E. Herrera. Dextran
sulfate complexes with potasium phosphate to interfere in determinations
of high-density lipoprotein cholesterol. Clin.Chem. 38: 233-237,
1992.
- Alvarez, J. J., M. A. Lasunción, J. M. Olmos, and E.
Herrera. Interindividual variation in the partition of lipoprotein(a)
into lipoprotein subfractions. Clin.Biochem. 26: 399-408, 1993.
- Bocos, C., M. Castro, G. Quack, and E. Herrera. Studies with
etofibrate in the rat. Part II: A comparison of the effects of
prolonged and acute administration on plasma lipids, liver enzymes
and adipose tissue lipolysis. Biochim.Biophys.Acta Lipids Lipid
Metab. 1168: 340-347, 1993.
- Entrala, A., M. Castro, M. A. Lasunción, E. Herrera,
and A. Sastre. Identificación de niveles plasmáticos
de las vitaminas A y E en un grupo de personas adultas sanas como
patrón de referencia para la población española.
Endocrinología 40: 71-74, 1993.
- Gómez-Coronado, D., G. T. Sáez, M. A. Lasunción,
and E. Herrera. Different hydrolytic efficiencies of adipose tissue
lipoprotein lipase on very-low-density lipoprotein subfractions
separated by heparin-Sepharose chromatography. Biochim.Biophys.Acta
Lipids Lipid Metab. 1167: 70-78, 1993.
- Herrera, E. and M. A. Lasunción. Estructura de las lipoproteínas
y apoproteínas. In Fernández Curz, A., ed. Monografías
clínicas en cardiología, nš 6: Lípidos y
corazón. Barcelona, Editorial Doyma. 1993, 9-27.
- Herrera, E., M. A. Lasunción, A. Montelongo, and A.
Martín. Maternal-fetal metabolic relationship. In Medina,
J. M. and J. Quero, eds. Physiologic basis of perinatal care.
Madrid, Ediciones Ergon. 1993, 15-27.
- Herrera, E., J. J. Alvarez, and M. A. Lasunción. Metabolismo
y fisiopatología de la lipoproteína(a). Nutr.Clín.
13: 7-24, 1993.
- Iglesias, A., J. A. Contreras, M. Martínez-Pardo, A.
Entrala, E. Herrera, and M. A. Lasunción. Cholesteryl ester
transfer activity in lipoprotein lipase deficiency and other primary
hypertriglyceridemias. Clin.Chim.Acta 221: 73-89, 1993.
- Lasunción, M. A., J. J. Alvarez, and E. Herrera. La
lipoproteína(a): de lipoproteína pre-beta oculta
a factor de riesgo cardiovascular. Med.Clin.(Barc). 101: 424-430,
1993.
- Lasunción, M. A. and E. Herrera. Bases del metabolismo
del colesterol. In Martín Zurro, A., ed. Hipercolesterolemias.
Problemas preventivos, diagnósticos y terapéuticos.
Barcelona, Editorial Doyma. 1993, 25-51.
- Martín, A., P. Ramos, and E. Herrera. Modulation of
lipoprotein lipase activity in adipose tissue during late pregnancy.
In Medina, J. M. and J. Quero, eds. Physiologic Basis of Perinatal
Care. Madrid, Ediciones Ergon. 1993, 117-122.
- Herrera, E., P. Ramos, P. López-Luna, and M. A. Lasunción.
Metabolic interactions during pregnancy in preparation for lactation.
In Serrano Ríos, M., A. Sastre, M. A. Perez Juez, A. Entrala,
and C. De Sabesti, eds. Dairy products in human health and nutrition.
Rotterdam, A.A. Balkema. 1994, 189-197.
- Herrera, E., C. Muñoz, P. Lopez-Luna, and P. Ramos.
Carbohydrate-lipid interactions during gestation and their control
by insulin. Brazilian J.Med.Biol.Res. 27: 2499-2519, 1994.
- Herrera, E. and M. A. Lasunción. Fisiopatología
del tejido adiposo blanco. In Soriguer Escofet, F. J. C., ed.
La Obesidad. Madrid, Ed. Díaz de Santos. 1994, 97-117.
- Iglesias, A., A. Montelongo, E. Herrera, and M. A. Lasunción.
Changes in cholesteryl ester transfer protein activity during
normal gestation and postpartum. Clin.Biochem. 27: 63-68, 1994.
- López-Luna, P., J. Olea, and E. Herrera. Effect of starvation
on lipoprotein lipase activity in different tissues during gestation
in the rat. Biochim.Biophys.Acta Lipids Lipid Metab. 1215: 275-279,
1994.
- Martin-Hidalgo, A., C. Holm, P. Belfrage, M. C. Schotz, and
E. Herrera. Lipoprotein lipase and hormone-sensitive lipase activity
and mRNA in rat adipose tissue during pregnancy. Am.J.Physiol.
266: E930-E935, 1994.
- Perales, J., M. A. Lasunción, A. Cano, M. A. Martín-Scapa,
M. Matíes, and E. Herrera. Cambios en el perfil lipídico
en hepatopatías crónicas. Med.Clin.(Barc). 102:
364-368, 1994.
- Bocos, C., E. Orozco, M. Castro, G. Quack, and E. Herrera.
Effect of etofibrate on bile production in the normolipidemic
rat. Gen.Pharmacol. 26: 537-542, 1995.
- Herrera, E. and C. Bocos. Papel de la nutrición en el
metabolismo del colesterol. In González Montero, M., ed.
Impacto de la nutrición en la biología humana. Madrid,
Universidad de Alcalá de Henares. 1995, 157-174.
- Martin, M. E., A. M. Garcia, L. Blanco, E. Herrera, and M.
Salinas. Effect of streptozotocin diabetes on polysomal aggregation
and protein synthesis rate in the liver of pregnant rats and their
offspring. Biosci.Rep. 15: 15-20, 1995.
- Muñoz, C., P. López-Luna, and E. Herrera. Glucose
and insulin tolerance tests in the rat on different days of gestation.
Biol.Neonate 68: 282-291, 1995.
- Ramos, P. and E. Herrera. Reversion of insulin resistance in
the rat during late pregnancy by 72-h glucose infusion. Am.J.Physiol.Endocrinol.Metab.
269: E858-E863, 1995.
- Ramos, P. and E. Herrera. Effect of prolonged glucose infusion
on insulin sensitivity in the conscious normal rat. Horm.Metab.Res.
27: 197-200, 1995.
- Wright, M. M., I. J. Lean, E. Herrera, and P. F. Dodds. Changes
in the composition of plasma very low density lipoprotein during
pregnancy and lactation in genetic lines of pigs. Animal Science
61: 361-368, 1995.
- Alvarez, J. J., A. Montelongo, A. Iglesias, M. A. Lasunción,
and E. Herrera. Longitudinal study on lipoprotein profile, high
density lipoprotein subclass, and postheparin lipases during gestation
in women. J.Lipid Res. 37: 299-308, 1996.
- Arranz, M. I., M. A. Lasunción, J. Perales, E. Herrera,
I. Lorenzo, C. Cárcamo, L. Concostrina, J. Villar, and
R. Gasalla. Fatty acid composition of lipoprotein lipids in hepatobiliary
diseases. Eur.J.Clin.Chem.Clin.Biochem. 34: 701-709, 1996.
- Blanco-Dolado, L., E. Herrera, and A. Martín-Hidalgo.
Actividad y expresión (ARNm) de la lipoproteína
lipasa y de la lipasa sensible a las hormonas en tejidos de ratas
vírgenes y preñadas diabéticas. Ars Pharmaceutica
37: 945-956, 1996.
- Bocos, C. and E. Herrera. Comparative study on the in vivo
and in vitro antilipolytic effects of etofibrate, nicotinic
acid and clofibrate in the rat. Eur.J.Pharmacol.Environ.Toxicol.Pharmacol.
2: 351-357, 1996.
- Bonet, B., M. Viana, and E. Herrera. Efectos teratogénicos
de la diabetes. Prevención con la administración
de antioxidantes. Ars Pharmaceutica 37: 1005-1010, 1996.
- Do Carmo, M. G. T., C. M. O. Do Nascimento, A. Martín-Hidalgo,
and E. Herrera. Effects of ethanol intake on lipid metabolism
in the lactating rat. Alcohol 13: 443-448, 1996.
- Garcia, A. M., M. E. Martin, L. Blanco, A. Martin-Hidalgo, J.
L. Fando, E. Herrera, and M. Salinas. Effect of diabetes on protein
synthesis rate and eukaryotic initiation factor activities in
the liver of virgin and pregnant rats. Biol.Neonate 69: 37-50,
1996.
- 282. Herrera, E. Lipid metabolism during gestation and its implications
for intrauterine development. In Battaglia, F., F. Falkner, C.
Garza, and B. Salle, eds. Maternal and extrauterine nutritional
factors. Their influence on fetal and infant growth. Madrid, Ediciones
Ergon, S.A. 1996, 115-126.
- 283. Herrera, E. Metabolismo lipídico durante la gestación.
Ars Pharmaceutica 37: 871-887, 1996.
- 284. Iglesias, A., M. Arranz, J. J. Alvarez, J. Perales, J.
Villar, E. Herrera, and M. A. Lasunción. Cholesteryl ester
transfer activity in liver disease and cholestasis, and its relation
with fatty acid composition of lipoprotein lipids. Clin.Chim.Acta
248: 157-174, 1996.
- 285. López-Luna, P., S. Martínez-Barrios, C. Muñoz,
and E. Herrera. Repercusiones metabólicas de la dieta rica
en sacarosa en la rata gestante ejercitada. Ars Pharmaceutica
37: 889-895, 1996.
- 286. López-Luna, P., R. Bernardo, and E. Herrera. Influencia
del ejercicio y la gestación sobre parámetros del
estrés oxidativo en rata. In Real Sociedad Española
de Historia Natural, ed. Tomo Extraordinario, 125 Aniversario
de la RSEHN. Madrid, Real Sociedad Española de Historia
Natural. 1996, 47-49.
- 287. Munilla, M. A. and E. Herrera. Efecto de una dieta rica
en colesterol en ratas preñadas y en sus fetos. Ars Pharmaceutica
37: 933-943, 1996.
- 288. Muñoz, C., P. López-Luna, and E. Herrera.
Effect of physical training on insulin response in late pregnancy
rats. Ars Pharmaceutica 37: 897-906, 1996.
- 289. Ramos, P. and E. Herrera. Comparative responsiveness to
prolonged hyperinsulinemia between adipose-tissue and mammary-gland
lipoprotein lipase activities in pregnant rats. Early Pregnancy:
Biol.and Med. 2: 29-35, 1996.
- 290. Soria, A., A. Chicco, N. Mocchiutti, R. A. Gutman, Y. B.
Lombardo, A. Martin-Hidalgo, and E. Herrera. A sucrose-rich diet
affects triglyceride metabolism differently in pregnant and nonpregnant
rats and has negative effects on fetal growth. J.Nutr. 126: 2481-2486,
1996.
- Tavares do Carmo, M. G., C. M. Oller do Nascimento, A. Martín-Hidalgo,
and E. Herrera. Effects of ethanol intake on lipid metabolism
in the lactating rat. Alcohol 13: 443-448, 1996.
- Viana, M., E. Herrera, and B. Bonet. Teratogenic effects of
diabetes mellitus in the rat. Prevention by vitamin E. Diabetologia
39: 1041-1046, 1996.
- Viana, M., C. Barbas, B. Bonet, M. V. Bonet, M. Castro, M.
V. Fraile, and E. Herrera. In vitro effects of a flavonoid-rich
extract on LDL oxidation. Atherosclerosis 123: 83-91, 1996.
- Barbas, C., M. Castro, B. Bonet, M. Viana, and E. Herrera.
Simultaneous determination of vitamins A and E in rat tissues
by high-performance liquid chromatography. J.Chromatogr.A 778:
415-420, 1997.
- Herrera, E. Metabolismo lipídico durante la gestación.
Alim.Nutri.Salud 4: 43-49, 1997.
- Herrera, E. and M. A. Munilla. Maternal lipid metabolism and
its implications for fetal growth. In Battaglia, F. C., ed. Placental
function and fetal nutrition. Philadelphia-New York, Lippincott-Raven.
1997, 169-182.
- Munilla, M. A. and E. Herrera. A cholesterol-rich diet causes
a greater hypercholesterolemic response in pregnant than in nonpregnant
rats and does not modify fetal lipoprotein profile. J.Nutr. 127:
2239-2245, 1997.
- Otero, P., M. Viana, E. Herrera, and B. Bonet. Antioxidant
and prooxidant effects of ascorbic acid, dehydroascorbic acid
and flavonoids on LDL submitted to different degrees of oxidation.
Free Radic.Res. 27: 619-626, 1997.
- Otero, P., E. Herrera, and B. Bonet. Factores aterogénicos
en adolescentes con diabetes mellitus insulinodependiente. Av.Diabetol.
13: 110-115, 1997.
- Alvarez, J. J. and E. Herrera. Bioquímica clínica
de la gestación. In González de Buitrago, J. M.,
E. Arilla Ferreiro, M. Rodríguez-Segade, and A. Sánchez
Pozo, eds. Bioquímica Clínica. Madrid, McGraw-Hill
Interamericana. 1998, 407-421.
- Barbas, C., M. Castro, and E. Herrera. A simplified measurement
of protein in natural latex. Alergy 53: 719-720, 1998.
- Barbas, C. and E. Herrera. Lipid composition and vitamin E
content in human colostrum and mature milk. J.Physiol.Biochem.
54: 167-174, 1998.
- Bocos, C. and E. Herrera. Pantethine stimulates lipolysis in
adipose tissue and inhibits cholesterol and fatty acid synthesis
in liver and intestinal mucosa in the normolipidemic rat. Environ.Toxicol.Pharmacol.
6: 59-66, 1998.
- Bonet, B., M. Viana, and E. Herrera. Efectos teratogénicos
de la diabetes: papel de los radicales libres. Endocrinología
45: 292-297, 1998.
- Carrascosa, J. M., P. Ramos, J. C. Molero, and E. Herrera.
Changes in the kinase activity of the insulin receptor account
for an increased insulin sensitivity of mammary gland in late
pregnancy. Endocrinology 139: 520-526, 1998.
- Herrera, E., B. Bonet, and M. A. Lasunción. Maternal-fetal
transfer of lipid metabolites. In Polin, R. A. and W. W. Fox,
eds. Fetal and neonatal physiology. Philadelphia, W.B.Saunders
Co. 1998, 447-458.
- Segade, and A. Sánchez Pozo, eds. Bioquímica Clínica.
Madrid, McGraw-Hill Interamericana. 1998, 395-405.
- López-Luna, P., M. A. Iglesias, C. Muñoz, and
E. Herrera. Aerobic exercise during pregnancy reverts maternal
insulin resistance in rats. Med.Sci.Sports Exerc. 30: 1510-1514,
1998.
- Relaño, E. and E. Herrera. Vías metabólicas
del piruvato que conducen a la formación de ácidos
orgánicos. In Bascones Martínez, A., ed. Tratado
de Odontología. Madrid, Smithkline Beecham,S.A. 1998, 479-498.
- Rupérez, F. J., C. Barbas, M. Castro, S. Martínez,
and E. Herrera. Simplified method for vitamin E determination
in rat adipose tissue and mammary glands by high-performance liquid
chromatography. J.Chromatogr.A 823: 483-487, 1998.
- Amusquivar, E. and E. Herrera. Efecto de variaciones en el contenido
graso de la dieta de la rata durante la gestación sobre
el perfil de ácidos grasos en plasma materno y fetal. Nutr.Hosp.
14: 114-119, 1999.
- 312. Do Carmo, M. G. T., C. M. O. Do Nascimento, A. Martin,
and E. Herrera. Ethanol intake during lactation impairs milk production
in rats and affects growth and metabolism of suckling pups. Alcohol
18: 71-76, 1999.
- Gómez-Coronado, D., J. J. Alvarez, A. Entrala, J. M.
Olmos, E. Herrera, and M. A. Lasunción. Apolipoprotein
E polymorphism in men and women from a Spanish population: allele
frequencies and influence on plasma lipids and apolipoproteins.
Atherosclerosis 147: 167-176, 1999.
- Herrera, E., E. Amusquivar, J. Rupérez, J. Cacho, and
C. Barbas. Estudio experimental sobre las ventajas del aceite
de oliva frente al de pescado durante la gestación, y sus
consecuencias en los fetos. Expoliva '99 IX (Sal-5): 1-14, 1999.
- Herrera, E. Metabolismo en el embarazo. In Hernández,
M. and A. Sastre, eds. Tratado de Nutrición. Madrid, Díaz
de Santos. 1999, 681-698.
- Muñoz, C., P. López-Luna, and E. Herrera. Treadmill
training enhances glucose tolerance more in pregnant than in virgin
rats. Biol.Neonate 75: 337-342, 1999.
- Ramos, P., A. Martín-Hidalgo, and E. Herrera. Insulin-induced
up-regulation of lipoprotein lipase messenger ribonucleic acid
and activity in mammary gland. Endocrinology 140: 1089-1093, 1999.
- Rupérez, F. J., C. Barbas, M. Castro, and E. Herrera.
Determination of a-tocopherol and a-tocopheryl acetate in diets
of experimental animals - Study of stability in the diets. J.Chromatogr.A
839: 93-99, 1999.
- Tavares do Carmo, M. G., C. M. Oller do Nascimento, A. Martin,
and E. Herrera. Ethanol intake during lactation impairs milk production
in rats and affects growth and metabolism of suckling pups. Alcohol
18: 71-76, 1999.
- Viana, M., C. Barbas, M. Castro, E. Herrera, and B. Bonet.
Alpha-tocopherol concentration in fetal and maternal tissues of
pregnant rats supplemented with alpha-tocopherol. Ann.Nutr.Metab.
43: 107-112, 1999.
- Amusquivar, E., F. J. Rupérez, C. Barbas, and E. Herrera.
Low arachidonic acid rather than a-tocopherol is responsible for
the delayed postnatal development in offspring of rats fed fish
oil instead of olive oil during pregnancy and lactation. J.Nutr.
130: 2855-2865, 2000.
- Herrera, E. Metabolic adaptations in pregnancy and their implications
for the availability of substrates to the fetus. Eur.J.Clin.Nutr.
54, Suppl. 1: S47-S51, 2000.
- Herrera, E., E. Amusquivar, and J. Cacho. Changes in dietary
fatty acids modify the decreased lipolytic b3-adrenergic response
to hyperinsulinemia in adipocytes frompregnant and nonpregnant
rats. Metabolism 49: 1180-1187, 2000.
- Herrera, E. and E. Amusquivar. Lipid metabolism in the fetus
and the newborn. Diabetes Metab.Res.Rev. 16: 202-210, 2000.
- Herrera, E. Metabolismo de la vitamina E. Nutrición y
Obesidad 3: 4-16, 2000.
- Herrera,E., M.A.Lasunción, L.Huerta,and A.Martín-Hidalgo.
Plasma leptin levels in mother and offspring during pregnancy.
Biol Neonate 78: 315-320, 2000.
- Klatt, P., J. Cacho, M. D. Crespo, E. Herrera, and P. Ramos.
Nitric oxide inhibits isoproterenol-stimulated adipocyte lipolysis
through oxidative inactivation of the b-agonist. Biochem.J. 351:
485-493, 2000.
- Munilla, M. A. and E. Herrera. Maternal hypertriglyceridemia
during late pregnancy is not added to the increase in circulating
triglycerides caused by long-term feeding a sucrose-rich diet
in the rat. J.Nutr. 130: 2883-2888, 2000.
- Panadero, M., E. Herrera, and C. Bocos. Peroxisome proliferator-activated
receptor-a expression in rat liver during postnatal development.
Biochimie 82: 723-726, 2000.
- Tibau de Alburquerque, K., M. G. Tavares do Carmo, and E. Herrera.
Ethanol consumption by lactating rats induces changes in pup's
fatty acid profiles. Alcohol 3: 331-337, 2000.
- Viana, M., O. I. Aruoma, E. Herrera, and B. Bonet. Oxidative
damage in pregnant diabetic rats and their embryos. Free Rad.Biol.Med.
29: 1115-1121, 2000.
- Dolnikoff, M., A. Martín-Hidalgo, U. F. Machado, F.
B. Lima, and E. Herrera. Decreased lipolysis and enhanced glycerol
and glucose utilization by adipose tissue prior to development
of obesity in monosodium glutamate (MSG) treated-rats. Int.J.Obes.
25: 426-433, 2001.
- Herrera, E. and C. Barbas. Vitamin E: action, metabolism and
perspectives. J.Physiol.Biochem. 57: 43-56, 2001.
- Panadero, M., H. Vidal, E. Herrera, and C. Bocos. Nutritionally
induced changes in the peroxisome proliferator-activated receptor-alpha
gene expression in liver of suckling rats are dependent on insulinemia.
Arch.Biochem.Biophys. 394: 182-188, 2001.
- Rupérez, F.J., E. Herrera, and C. Barbas. Analysis of
a-tocopherol and related compounds in various chromatographic
matrices. J. Chromatogr. A. 935, 45-69, 2001
- López-Soldado, I., A. Munilla, and E. Herrera. A sucrose-rich
diet during pregnancy causes a similar response in Sprague-Dawley
and Wistar rats. Ann. Nutr. Metab. 45, 285-290, 2001.
- Soria, A., Bocos, C., and Herrera, E. Opposite metabolic response
to fenofibrate treatment in pregnant and virgin rats. Journal
of Lipid Research . 43, 74-81, 2002
- Blanco-Dolado, L., Martín-Hidalgo, A., and E. Herrera.
Streptozotocin-induced diabetes decreases mammary gland lipoprotein
lipase activity and messenger ribonucleic acid in pregnant and
nonpregnant rats. Int. Jnl. Experimental Diab. Res. 3, 61-68,
2002
- Gómez-Coronado, D., Entrala, A., Álvarez, J.J.,
Ortega, H., Olmos, J.M., Castro, M., Sastre, A., Herrera, E.,
and Lasunción, M.A. Influence of apolipoprotein E polymorphism
on plasma vitamin A and vitamin E levels. Eur. J. Clin. Invest.
32, 251-258, 2002
- Herrera, E. Implications of dietary fatty acids during pregnancy
on placental, fetal and postnatal development. Placenta 23, Sppl.
A, S9-S19, 2002
- Martínez, S., Barbas, C., and Herrera, E. Uptake of
a-tocopherol by mammary gland although not by white adipose tissue
is dependent on lipoprotein lipase activity around parturition
and during lactation in the rat. Metabolism 51, 000-000, 2002
- López-Soldado, I., Betancor-Fernández, A., and
Herrera, E.: Differential metabolic response to 48 h food deprivation
at different times of pregnancy in the rat. J. Physiol. Biochem.
58, 75-86, 2002
- Herrera, E.: Lipid metabolism in pregnancy and its consequences
in the fetos and newborn. Endocrine 19, 000-000, 2002
- Beysen, C.B., Belcher, A.K., Karpe, F., Fielding, B.A., Herrera,
E., and Frayn, K.N.: Novel experimental protocol to increase specific
plasma nonesterified fatty acids in humans. Am. J. Physiol. Endocrinol.
Metab. 284, E000-E000, 2003.
- Ramos, M.P., Crespo-Solans, M.D., del Campo, S., and Herrera,
E.: Fat accumulation in the rat during early pregnancy is modulated
by enhanced insulin responsiveness. Am. J. Physiol. Endocrinol.Metab.
In Press.
- Amusquivar, E., and Herrera, E.: Influence of changes in dietary
fatty acids during pregnancy on placental and fetal fatty acid
profile in the rat. Biol. Neonate. In Press
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Pilar
Ramos
Full name : Ma
del Pilar Ramos Alvarez
Born in Madrid (Spain), 1st June 1964
Current position:
Professor of Biochemistry and Molecular Biology,
Faculty of Experimental
and Health Sciences,
Universidad San Pablo-CEU,
Madrid, Spain.
Academic
and research activities:
Study of Biology (1982-1987) at the Universidad Autónoma
de Madrid
Master's degree in Science (Biology), Universidad Autónoma
de Madrid,
1989.
Ph.D. in Science (Biology), Universidad Autónoma de Madrid, 1993.
Postdoctoral studies (1994-96): Institute of Biochemistry,
Karl-Franzens University, Graz,.Austria
Assistant Professor of Biochemistry and Molecular Biology, Universidad San Pablo-CEU,
from 1996.
Prizes and research distinctions:
Research
award (as supervisor) of Fundación San Pablo-CEU,
1998
Research award of Fundación San Pablo-CEU, 1999
Research award (as supervisor), Cátedra Leche Pascual,
2001
Master theses supervised: 2 (+ 3 under
supervision)
Publications:
In scientific journals and book chapters: 23
Presentations to Scientific Congresses (Abstracts): 71; Published
abstracts: 11
Current Scientific Projects
Role of nitric oxide in the development of insulin resistance.
Support: Ministerio de Ciencia y Tecnología. PM99/001
Duration: 2000-2003.
Principal Investigator: Ma del Pilar Ramos.
Insulin, dietary fatty acids and peroxisomal proliferator activated
receptors (PPARs): interactions in pregnancy and perinatal development
Support. Fundación Universitaria San Pablo-CEU, CEU10/01:
Duration: 2001-2003.
Principal Investigator: Emilio Herrera.
Dietary fat, body weight control and links between obesity and
cardiovascular disease.
Support: Unión Europea , FAIR-CT-98-4141.
Duration: 1999-2002
Principal Investigator: Emilio Herrera..
Consequences of modifying dietary fatty acids on muscle and adipose
tissue insulin responsiveness in pregnant rats
Support: Programa de Cooperación Científica con Iberoamérica
2000
Duration: 2000-2002
Principal Investigator: E. Herrera.
Role of dietary fatty acids and the peroxisomal proliferator activated
receptors (PPARs) insulin resistance and diabetes predisposition
in pregnancy
Support: Comunidad de Madrid, 08.6/0023/2000:
Duration: 2001-2003.
Principal Investigator: Emilio Herrera..
Original Papers:
- E. Herrera, C. Muñoz, P. López-Luna
and P. Ramos. Carbohydrate-lipidic interactions during gestation
and its control
by insulin. Brazilian Journal
of Medical and Biological Research 27, 2499-2519, 1994.
- H. Esterbauer,
S. Gieseg, A. Giessau, O. Ziouzenkova and P.Ramos.
Free radicals and oxidative modification of LDL Role of natural
antioxidants.
Atherosclerosis X, 203-208,1995.
- P.Ramos and E.Herrera. Effect of prolonged
glucose infusion on insulin sensitivity in the concious normal
rat. Horm.Metab.Res. 27, 197-200, 1995.
- P.Ramos, S.P.Gieseg, B.
Schuster and H.Esterbauer. Temperature dependence of copper-mediated
oxidation of low density lipoprotein.
J.Lipid Res. 36,
2113-2128, 1995.
- H. Esterbauer and P. Ramos. Chemistry and pathophysiology
of oxidation of LDL. Rev.Physiol.Biochem.Pharmacol. 127, 31-64,
1996.
- P.Ramos and E.Herrera. Reversion of insulin resistance in
the rat during late pregnancy by 72-h glucose infusion. Am.J.Physiol.
269: E858-E863, 1995.
- P.Ramos and E.Herrera. Comparative responsiveness
to prolonged hyperinsulinemia between adipose tissue and mammary
gland lipoprotein
lipase activities in
pregnant rats. Early Pregnancy: Biology and Medicine, 2: 29-35, 1996.
- O.Ziouzenkova,
S.P.Gieseg, P. Ramos and H. Esterbauer. Factors affecting resistance
of LDL to oxidation. Lipids 31, S71-S76, 1996.
- W.Sattler, H.Reicher,
P. Ramos, U.Panzenboeck, M.Hayn, H. Esterbauer, E.Malle and G.Kostner.
Preparation of fatty acid
methyl esters from lipoprotein
and
macrophage lipid subclasses on thin-layer plates. Lipids, 31, 1303-1310,
1996.
- M. Kveder, G.Pifat, S. Pecar, M.Schara, P.Ramos and H. Esterbauer.
Nitroxide reduction with ascorbic acid in spin labeled human
plasma LDL and VLDL. Chem
Phys. Lipids 85, 1-12, 1997.
- M. Kveder, G.Pifat, S. Pecar, M.Schara, P.Ramos
and H. Esterbauer. The interaction of lower alcohols with apo
B in spin labeled human plasma
low
density lipoproteins (LDL). Chem Phys. Lipids 87,125-135, 1997.
- R. Albertini,
P. Ramos, A. Giessauf, A. Passi, G. De Luca, H. Esterbauer. Chondroitin
4-sulphate exhibits inhibitory effect during Cu2+- mediated
LDL oxidation. FEBS Lett. 403, 154-158, 1997.
- A.R. Bergmann, P.
Ramos, H.Esterbauer and B.M.Winklhofer-Roob. a-tocopherol
can be substituted for by trolox in determination of kinetic
parameters
of LDL oxidizability by copper. J.Lipid Res. 38, 2580-2588, 1997.
- J.M.
Carrascosa, P. Ramos, J.C. Molero y E. Herrera. Changes in the
kinase activity of the insulin receptor account for an increased insulin
sensitivity
of mammary gland in late pregnancy. Endocrinol. 139, 520-526, 1998.
- O.
Ziouzenkova, A. Sevanian, P. Abuja, P. Ramos, H. Esterbauer.
Copper can promote oxidation of LDL by markedly different mechanism.
Free Rad.
Biol. Med., 24(4): 607-623, 1998.
- G. Jeglitsch, P. Ramos, A. Encabo, H.A.
Tritthart, H. Esterbauer, K. Grosner, W. Schreibmayer. The cardiac
acetylcholine-activated, inwardly
rectifying
K+-channel
subunit GIRK1 gives rise to an inward current induced by free oxygen
radicals Free Rad. Biol. Med., 26(3-4): 253-259, 1999.
- P. Ramos, A. Martín-Hidalgo,
E. Herrera. Insulin-induced upregulation of lipoprotein lipase mRNA
and activity in mammary gland. Endocrinol.
140 (3): 1089-93, 1999.
- P. Klatt, J. Cacho,
M.D. Crespo,E. Herrera, P. Ramos. Nitric oxide inhibits isoproterenol-stimulated
lipolysis
through oxidative inactivation
of the
b-agonist. Biochem. J. 351 (2): 485-493, 2000.
- M.P.Ramos, M.D. Crespo-Solans,
S. del Campo, J. Cacho, E. Herrera. Fat accumulation in the
rat during early pregnancy is modulated by
insulin responsiveness.
Am.J.Physiol. (in press)
Book Chapters:
- E. Herrera, P.Ramos
and A.Martín. Control by insulin
of adipose tissue lipoprotein lipase activity during late gestation
in the rat. Frontiers in
Diabetes Research. Lessons from animal diabetes III., cap.XI.6.; 551-554,
Ed.E.Shafrir, Londres. 1991
- Martin A.; Ramos
P. and Herrera . Modulation of lipoprotein lipase activity
in adipose tissue during late pregnancy. Physiologic
Basic of Perinatal Care.
117-123, Ediciones Ergón S.A. Madrid, 1993.
- E.Herrera; P.Ramos;
P. López-Luna; M.A.Lasunción. Metabolic
interactions during pregnancy and in preparation for lactation. Dairy Products
in Human Health and Nutrition, 189-197, ed. Serrano Ríos et al.
Editorial Balkema, Rotterdam, 1994.
- H. Esterbauer, S.Gieseg, A. Giessauf,
O.Ziouzenkova and P.Ramos. Role
of natural antioxidants in inhibiting copper mediated oxidations of LDL.
Free
radicals, lipoprotein oxidation and atherosclerosis, 11-26, ed. G. Bellomo,
G. Finardi, E. Maggi and C. Rice-Evans. Richelieu Press, London, 1995.
Published Abstracts:
- 1. Ramos P.; Herrera E.: Efecto de la insulina en las actividades
de la lipoproteína
lipasa de distintos tejidos en la rata. Clinica e Investigación en
Arterosclerosis. Vol.2, pp 33 (1990).
- P.Ramos; A.Martín; E.Herrera: Papel de la insulina
en el control de la actividad lipoproteína lipasa del
tejido adiposo durante la gestación.
Avances en Diabetología Vol.3.pp 32. (1990).
- E.Herrera; P.Ramos: Continuous hyperinsulinemia reverts insulin
resistance in the rat during late gestation. Diabetologia Vol.34,
pp A197. (1991).
- E. Herrera; P.Ramos: Insulin Resistance during late gestation
is responsible for low lipoprotein lipase activity in maternal
adipose tissue. Diabetes
40, pp 138A. (1991).
- P.Ramos; A.Martín; E.Herrera: Role of insulin on lipoprotein
lipase activity in mammary gland during gestation in the rat.
Diabetologia 35.
177A (1992).
- E. Herrera, P. Ramos, L. Blanco and A.Martín: Enhanced
response to insulin in mammary gland during late gestation in
the rat. Diabetologia
Vol.36,
A167 (1993). A. Martín-Hidalgo, P. Ramos and E. Herrera. Hyperinsulinemia
enhances lipoprotein lipase activity and mRNA expression in both
adipose tissue and
mammary gland of pregnant rats. Diabetologia 39, A163 (1996).
- Herrera E.,
Amusquivar E., Cacho J., Ramos P., Expresión
de receptores b3-adrenérgicos
en adipocitos de ratas preñadas
y papel de la insulina y los ácidos grasos de la dieta
en su respuesta lipolítica.
Endocrinología 46, 12 (1999)
- Ramos P., M.D. Crespo, Herrera E., b3-Adrenoceptor
expression in white adipose tissue during pregnancy. Biochemie
81, s-306
(1999).
- Herrera E., M.D. Crespo, Ramos P. b3-Adrenoceptors
in adipose tissue are modulated by hyperinsulinemia and insulin
sensitivity during pregnancy.
Diabetologia
43, A-215 (2000).
- M.V. Cano, L. Ezquerra, M.P. Ramos, M. Ruiz-Gayo. Cholecystokinin
differently regulates insulin release in fed and fasted rats. Methods
and Findings
in Experimental and Clinical Pharmacology 24, A-157 (2002).
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Encarnación
Amusquivar
Born in Madrid (Spain), 25th April 1970
Current position:
Assistant Professor of Biochemistry,
Faculty of Experimental and Health Sciences,
Universidad San Pablo CEU,
Madrid, Spain.
Academic and research activities:
Degree in Food Science and Technology, Universidad del País
Vasco (1988-1992).
Master´s degree in Clinical Nutrition, Universidad Autónoma
de Madrid, 1994.
PhD in Food Science and Techonology, Universidad San Pablo-CEU,
Madrid, 2001.
Assistant Professor of Biochemistry, Universidad San Pablo-CEU,
from 1999.
Prizes and research distinctions:
Research award of Fundación San Pablo-CEU as participant
in ‘Biochemistry and Metabolism Group’, 1999.
PhD Thesis award of Universidad San Pablo-CEU, 2002.
Research award (as supervisor), Cátedra Leche Pascual, 2002.
Original Papers:
1. E. Amusquivar, E. Herrera. “Efecto de variaciones en el
contenido graso de la dieta de la rata durante la gestación
sobre el perfil de ácidos grasos en plasma materno y fetal”.Nutr
Hosp. (1999) XIV (3) 114-119.
2. E. Herrera, E. Amusquivar, J. Cacho. “Changes in Dietary
Fatty Acids Modify the Decreased Lipolytic b3-Adrenergic Response
to Hiperinsulinemia in Adipocytes from Pregnant and Nonpregnant
Rats”. Metabolism (2000); 49:1180-1187.
3. E. Herrera, E. Amusquivar. “Lipid metabolism in the fetus
and the newborn”. Diabetes Metab Res Rev (2000); 16: 202-210.
4. E. Amusquivar, F.J. Rupérez, C. Barbas, E. Herrera. “Low
arachidonic acid rather than a-tocopherol is responsible for the
delayed postnatal development in offspring of rats fed fish oil
instead of olive oil during pregnancy and lactation”. J Nutr
(2000); 130 :2855-2865.
5. E. Amusquivar, E. Herrera: Influence of changes in
dietary fatty acids during pregnancy on placental and
fetal fatty
acid profile
in the rat. Biol. Neonate (2003); 83: 136-145.
6. E. Amusquivar, E. Herrera: Influencia de los ácidos grasos
de la dieta en su distribución entre las lipoproteínas
circulantes y en su asequibilidad al feto en la rata preñada.
Clin Invest Arterioscl 2003,15(3):91-8.
Presentations
to scientific congresses (Abstracts): 27
Current Scientific Projects:
Insulin, dietary fatty acids and peroxisomal proliferator
activated receptors (PPARs): interactions in pregnancy
and perinatal
development
Support. Fund
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