Gernot DESOYE

Scientific curriculum vitae

Research Awards

Elected/honorary memberships

Reviewer activities

Current funding

European Community QLRT-2001-00138: ‘PERILIP: Influence of Dietary Fatty Acids on the Pathophysiology of Intrauterine Foetal Growth and Neonatal Development’; € 330.000 partner

FWF 13321: Heterogeneity of endothelial cells isolated from the human term placenta; € 100.000; principal investigator

ÖNB 8339: Effects of hyperglycemia in vitro on proliferation and invasion of human first trimester trophoblast cells € 22.000; principal investigator

ÖNB 8775: ‘Hypoxia regulates effects of endothelin-1 in the human placenta’; € 73.000; co-investigator

ÖNB 8776: ‘Human trophoblast cells of distinct stages in first trimester respond differently to diabetes-associated hyperglycemia: In vitro studies to identify underlying mechanisms’; € 73.000; co-investigator

ÖNB 9057:’Insulin-effects on the human placenta’; € 60.000; co-investigator

ÖNB 9653: ‘Regulation of glykogenin expression in the human placenta by hyperglycemia’; € 80.000; co-investigator

British Council Vienna: Exploratory grant together with R. Leach, Nottingham, UK.

Scientific areas of interest

1) Impact of maternal diabetes on placental metabolism and development

2) Trophoblast invasion in man

3) Glucose transport across the human placenta

4) Insulin receptors and insulin effects in the human placenta

5) Role of endothelin-1 in the development of pre-eclampsia

Back to Graz Page

List of publications
(* indicates independent work)

1. Schauenstein E, Saenger W, Schaur RJ, Desoye G, Schreibmayer W. Der Einfluss des pH, der Temperatur und der Polarität des Lösungsmittels auf die Absorption des reduzierten und oxidierten Nicotinamid-adenin-dinukleotides bei 260 nm. Z. Naturforsch. 1980; 35c: 76-79
2. Schauenstein E, Desoye G, Nöhammer G. Quantitative Proteinbestimmung in Einzelzellen mit Amidschwarz. Histochem. 1980, 68: 75-90.
3. Desoye G, Pörschke D. Polynucleotide - Oligopeptide - Interactions. studio biophys 1980; 81: 107-108.
4. Desoye G, Schauenstein E. Modellversuche zur quantitativen Cytophotometrie mit Proteinfilmen. Micros Acta 1981; 84: 9-16
5. Nöhammer G, Desoye G. The cytospectrophotometrical determination of proteins by the tetrazonium coupling reaction II. Calibration of the staining method. Acta Histochem 1981; 68: 103-110.
6. Nöhammer G, Desoye G, Koschsorur G. Quantitative cytospectrophotometrical determination of the total protein thiols with mercurochrom. Optimization and calibration of the histochemical reaction. Histochem. 1981; 71: 291-300.
7. Zechner R, Desoye G, Schweditsch MO, Pfeiffer KP, Kostner GM. Fluctuations of plasma lipoprotein - (a) concentrations during pregnancy and post partum. Metabolism 1986; 35: 333-336.
8. Leiner M, Schaur RJ, Wolfbeis OS, Desoye G. Fluorescence topography in biology III. Characteristic deviations of tryptophane fluorescence in sera of patients with gynecological malignancies. Clin Chem 1986; 32: 1974-1978.
9. *Desoye G, Weiss PAM. Influence of the lipid environment on insulin binding to placental membranes from normal and diabetic mothers. Trophoblast Res 1987; 2: 29-43.
10. Flaschka G, Desoye G. CEA plasma levels in patients with intracranial tumors. Neurochirurgia 1987; 30: 5-7.
11. *Desoye G, Schweditsch MO, Pfeiffer KP, Zechner R, Kostner GM. Correlation of hormones with lipid and lipoprotein levels during normal pregnancy and post partum. J Clin Endocrinol Metab 1987; 64: 704-712.
12. Dohr GA, Motter W, Leitinger W, Desoye G, Urdl W, Winter R, Wilders-Truschnig, MM, Uchanska-Ziegler B, Ziegler A. Lack of expression of histocompatibility leucocyte antigen class I and class II molecules on the human oocyte. J Immunol 1987; 138: 3766-3770.
13. * Desoye G. Error analysis in equlibrium dialysis: Evaluation of adsorption phenomena. J Biochem Biophys Meth 1988; 17: 3-16.
14. * Desoye G, Dohr GA, Motter W, Winter R, Urdl W, Pusch H, Uchanska-Ziegler B, Ziegler A. Lack of HLA class I and class II antigens on human preimplantation embryos. J Immunol 1988; 140: 4157-4159.
15. Mayer HO, Kostner G, Tscherne G, Desoye G. Vergleich des Einflusses eines Desogestrel- bzw. Levonorgestrelhaltigen Kombinationspräparates auf Lipid- Stoffwechsel, Serumtestosteron und SHBG. Fertilität 1988; 4: 173-178.
16. Beham A, Denk H, Desoye G. The distribution of intermediate filament proteins, actin and desmoplakins in human placental tissue as revealed by polyclonal and monoclonal antibodies. Placenta 1988; 9: 479-492.
17. *Desoye G. Measurement of non-specific binding by parallel or consecutive incubation procedures in receptor homogenates following tissue disintegrations by sonification. J. Biochem Biophys Methods 1990; 17: 3-16.
18. Flaschka G, Marth E, Desoye G, Freidl W, Walzl M. Diagnostische Wertigkeit biochemischer Tumormarker bei Hirntumoren. Zent. bl. Neurochir. 1990; 51: 129-137
19. *Desoye G, Dohr G, Ziegler A. Expression of human major histocompatibility antigens on germ cells and preimplantation embryos. Lab Invest 1991; 64: 306-312.
    
20. *Desoye G, Ertl-Stockinger U, Porta S. Prolonged administration in vivo of a- and b-adrenergic agonists decreases insulin binding to rat myocardial membranes in vitro by different mechanisms. Life Sci. 1991; 48: 2249 - 2258.
21. *Schmon B, Hartmann M, Jones CJ, Desoye G. Insulin and glucose do not affect the glycogen content in isolated and cultured trophoblast cells of human term placenta. J Clin Endocrinol Metabol 1991; 73: 888-893
22. Urdl W, Desoye G, Schmon B, Hofmann HMH, Ralph G. Interactions between insulin and insulin-like growth factor I in the pathogenesis of polycystic ovarian disease. Ann NY Acad Sci 1991; 626: 177-183.
23. *Desoye G, Hofmann HMH, Weiss PAM. Insulin binding to trophoblast plasma membranes and placental glycogen content in well-controlled gestational diabetic women treated with diet or insulin, in well-controlled overt diabetic patients and in healthy control subjects. Diabetologia 1992; 35: 45-55.
24. *Desoye G, Schmon B, Gmoser G, Friedl H, Urdl W, Weiss PAM. Insulin binding to red blood cells of nonpregnant women: A re-evaluation, underlining the importance of body weights even in nonobese subjects. Clin. Chim. Acta, 1992; 207: 57-71.
25. *Desoye G, Schmon B, Hartmann M, Dohr G, Flaschka G, Jones CJ Opposite effects of an antilipolytic hormone (nicotinic acid) on the production/secretion of hCG and hPL by isolated trophoblast cells. Trophoblast Res 1992; 6: 199-210.
26. Desoye G, Pörschke D. Structure and Dynamics of peptide-polynucleotide complexes. Biophys Chem 1993; 46: 283-294.
27. * Lang I, Hartmann M, Blaschitz A, Dohr G, Skofitsch G, Desoye G. Immunohistochemical evidence for the heterogeneity of maternal and fetal vascular endothelial cells in human full term placenta. Cell Tissue Res 1993; 274: 211-218.
28. Jones CJP, Desoye G. Glycogen distribution in the capillaries of the placental villus in normal, overt and gestational diabetic pregnancy. Placenta 1993; 14: 505-517.
29. Wolf HJ, Desoye G. Immunohistochemical localization of glucose transporters and insulin receptors in human fetal membranes at term. Histochem 1993; 100: 379-385.
30. *Desoye G, Barnea E, Shurz-Swirsky R. The sulfonylurea glipizide decreases the phospholipid content and increases insulin binding of human term placental homogenates. Biochem Pharmacol 1993; 46: 1585-1590.
31. Hahn T, Desoye G, Lang I, Skofitsch G. Location and activities of acetylcholinesterase and butyrylcholinesterase in the rat and human placenta. Anat Embryol 1993; 188: 435-440.
32. *Schmon B, Desoye G, Friedl H, Hofmann H, Weiss PAM, Hagmüller K. Insulin receptor binding on red blood cells in early pregnancy is increased in healthy pregnant women compared to non-pregnant or gestational diabetic women. Clin Chim Acta 1993; 221: 33-46.
33. Jones CJP, Hartmann M, Blaschitz A, Desoye G. Ultrastructural localization of insulin receptors in human placentae. Am J Reprod Immunol 1993; 30: 136-145.
34. *Desoye G, Hartmann M, Blaschitz A, Dohr G, Kohnen G, Kaufmann P. Insulin receptors in syncytiotrophoblast and fetal endothelium of human placenta. Immunohistochemical evidence for developmental changes in distribution pattern. Histochem 1994; 101: 277-285.
35. Hahn T, Graf R, Desoye G, Öney T. Effects of the synthetic glucocorticoid triamcinolone acetonide on vasoactive hydrolases of the human placenta in vitro. Placenta 1994; 15: 377-388.
36. Frank H-G, Malekzadeh F, Kertschanska S, Crescimanno C, Castellucci M, Lang I, Desoye G, Kaufmann P. Immunohistochemistry of two different types of placental fibrinoid. Acta Anatomica 1994; 150: 55-68.
37. *Hahn T, Blaschitz A, Hartmann M, Lang I, Skofitsch G, Dohr, G, Desoye G. Non-Michaelis-Menten kinetics of zero-trans glucose uptake by trophoblast cells from human term placentae and by choriocarcinoma (JEG-3/JAR) cells. Biol Chem Hoppe-Seyler 1994; 375: 543-550.
38. *Lang I, Hartmann M, Blaschitz A, Dohr G, Kaufmann P, Frank H-G, Hahn T, Skofitsch G, Desoye G. Differential lectin binding to the fibrinoid of human full term placenta: Correlation with a fibrin antibody and the PAF-HALMI method. Acta Anatomica 1994; 150: 170-177.
39. * Lang I, Hahn T, Dohr G, Skofitsch G, Desoye G. Histochemical reaction pattern of the lectin bandeiraea (Griffonia) simplicifolia with blood vessels of human full term placenta is independent of the blood group. Cell Tiss Res 1994; 278: 433-438.
40. * Hahn T, Hartmann M, Blaschitz A, Skofitsch G, Graf R, Dohr G, Desoye G. Localisation of the high affinity facilitative glucose transporter protein GLUT 1 in human, marmoset-monkey (Callithrix jacchus) and rat placentae at different developmental stages. Cell Tissue Res 1995; 280: 49-57.
41. Haidacher S, Blaschitz A, Desoye G, Dohr G. Immunohistochemical evidence of p53 protein in human placenta and choriocarcinoma cell lines. Human Reprod 1995; 10: 983-988.
42. *Cervar M, Kainer F, Desoye G. Pre-eclampsia and gestational age differently alter binding of endothelin-1 to placental and trophoblast membrane preparations. Mol Cell Endocrinol 1995; 110: 65-71.
43. *Cervar M, Kainer F, Jones CJP, Desoye G. Pre-eclampsia affects the release of endothelin-1,2 and thromboxane B2 but not of leukotriene B4 and angiotensin II from preterm and term human trophoblast cells. Eur J Clin Invest 1996; 26: 30-37.
44. *Cervar M, Puerstner P, Kainer F, Desoye G. Endothelin-1 stimulates the proliferation and invasion of first trimester trophoblastic cells in vitro: A possible role in the etiology of pre-eclampsia? J Investig Med 1996; 44: 447-453.
45. *Cervar M, Nelson DM, Kainer F, Desoye G. Drug actions in preclampsia: aspirin, but not MgCl₂ or dihydralazine, differentially inhibits human trophoblast release of thromboxane and prostacyclin without affecting angiotensin II, endothelin-1 or leukotriene B₄ secretion. Am J Obstet Gynecol 1997; 176: 66-72.
46. Nöhammer G, Desoye G. Mercurochrom can be used for the histochemical demonstration and microphotometric quatitation of both protein thiols and protein (mixed) disulfides. Histochem Cell Biol 1997; 107: 383-390.
47. Schneider H; Desoye G. Strukturelle und funktionelle Veränderungen bei Diabetes in der Schwangerschaft. Gynäkologe 1998; 31: 173-181.
48. Halwachs-Baumann G, Wilders-Truschnig M, Desoye G, Hahn T, Kiesel L, Klingel K, Rieger P, Jahn G and Sinzger C. Human trophoblast cells are permissive to the complete replicative cycle of human cytomegalovirus. J Virol 72, 7598-7602, 1998
49. *Hahn T, Barth S, Mosgoeller W, Desoye G. Sustained hyperglycemia in vitro downregulates the GLUT1 glucose transport system of cultured human term placental trophoblast. - A mechanism to protect fetal development? FASEB J 12, 1221-1231, 1998
50. *Hahn T, Barth S, Hofmann W, Reich O, Steiner B, Desoye G. Hyperglycemia regulates the glucose transport system of clonal choriocarcinoma cells in vitro. Int J Cancer 78, 353-360, 1998
51. *Cervar M, Desoye G. The endothelin/endothelin receptor system of human trophoblast in normal and pre-eclamptic pregnancies. Trophoblast Res 1998; 12:341-357.
52. *Cervar M, Blaschitz A, Dohr G, Desoye G. Paracrine regulation of distinct trophoblast functions in vitro by placental macrophages. Cell Tiss Res. 1999, 295: 297-305
53. *Hahn T, Barth S, Graf R, Engelmann M, Beslagic D, Reul JM, Holsboer F, Dohr G, Desoye G. Placental glucose transporter expression is regulated by glucocorticoids. J Clin Endocrinol Metabol. 1999, 84:1445-1452
54. Hahn T, Hahn D, Blaschitz A, Korgun ET, Desoye G, Dohr G. Hyperglycaemia-induced subcellular redistribution of GLUT1 glucose transporters in cultured human term placental trophoblast cells. Diabetologia 2000, 43: 173-180
55. Bilban M, Head S, Desoye G, Quaranta V. DNA microarrays: A novel approach to investigate genomics in trophoblast invasion. Placenta 2000; 21: S99-S105.
56. Wolf HJ, Ebenbichler CF, Huter O, Bodner J, Lechleitner M, Föger B, Patsch JR, Desoye G. Fetal leptin and insulin levels only correlate in large-for-gestational age infants. Eur J Endocrinol 2000; 142: 623-629.
57. *Cervar M, Huppertz B, Barth S, Hahn T, Weiss U, Kaufmann P, Desoye G. Endothelin A and B receptors change their expression levels during development of human placental villi. Placenta 2000; 21: 536:546
58. *Blaschitz A, Weiss U, Dohr G, Desoye G. Antibody Reaction Patterns in First Trimester Placenta: Implications for Trophoblast Isolation and Purity Screening. Placenta 2000; 21: 733-741
59. *Bilban M, Barth S, Cervar M, Mauschitz R, Schaur RJ, Desoye G. Differential regulation of endothelin secretion and endothelin receptor mRNA levels in JAR, JEG-3 and BeWo choriocarcinoma cell lines and in human trophoblast, their non-malignant counterpart. Arch Biochem Biophys 2000; 382: 245-252
60. *Mauschitz R, Cervar M, Hahn T, Pürstner P, Desoye G. Self-regulation of the endothelin receptor system in choriocarcinoma cells. Biochim Biophys Acta 2000; 1502:224-234.
61. *Weiss U, Cervar M, Pürstner P, Schmut O, Haas J, Mauschitz R, Desoye G. Hyperglycemia in vitro alters the proliferation of choricarcinoma cell lines BeWo, JAR and JEG-3 as models for human first trimester trophoblast. Diabetologia 2001 44:209-219
62. *Jones CJP, Weiss U, Siman CM, Desoye G. Mitochondria from human trophoblast and embyronic liver cells are intrinsically resistant to hyperglycaemia-associated high-amplitude swelling. Diabetologia 2001, 44: 389-391
63. Hammer A, Desoye G, Dohr G, Sattler W, Malle E. Myeloperoxidase-dependent generation of hypochlorite-modified proteins in human placental tissues during normal pregnancy. Lab Invest 2001, 81:543-554
64. *Lang I, Hoffmann C, Olip H, Pabst MA, Hahn T, Dohr G, Desoye G. Differential mitogenic responses of human macrovascular and microvascular endothelial cells to cytokines underline their phenotypic heterogeneity. Cell Proliferation 2001, 34: 143-155
65. Korgun ET, Demir R, Hammer A, Dohr G, Desoye G, Skofitsch G, Hahn T. Glucose transporter expression in rat embryo and uterus during decidualization, implantation and early post-implantation. Biology of Reproduction 65: 1364-1370, 2001
66. Hahn D, Blaschitz A, Korgun ET, Lang I, Desoye G, Skofitsch G, Dohr G. From maternal glucose to fetal glycogen: Expression of key regulators in the human placenta. Mol. Hum. Reprod. 2001; 7: 1173-1178.
67. Arikan G, Reich O, Weiss U, Hahn T, Reinisch S, Tamussino K, Pickel H, Desoye G. Are endometrial carcinoma cells disseminated at hysteroscopy functionally viable? Gynecol. Oncol. 83: 221-226 (2001)
68. Korgun ET, Demitr R, Sedlmayr P, Desoye G, Arikan GM, Puerstner P, Häusler M, Dohr G, Skofitsch G, Hahn T. Sustained hypoglycemia affects glucose transporter expression of human blood leukocytes. Blood Cells Mol Dis 28: 152-159 (2002)
69. Bilban M, Buehler LK, Head S, Desoye G, Quaranta V. Normalizing DNA microarray data. Curr Issues Mol Biol. (2002) 4:57-64
70. Mandl M, Haas J, Bischof P, Nöhammer G, Desoye G. IGF-I and insulin effects on model cell lines for first trimester trophoblast are modified by serum. Histochem Cell Biol 117:391-9 (2002)
71. Desoye G, Korgun ET, Ghaffari N, Hahn T. Is fetal macrosomia in adequately controlled diabetic women the result of a placenta defect? - a hypothesis. J Maternal Fetal Neonatal Medicine 11: 258-261 (2002)
72. Korgun ET, Demir R, Sedlmayr P, Desoye G, Arikan G, Pürstner P, Häusler M, Dohr G, Skofitsch G, Hahn T. Physiological leukocytosis during pregnancy is associated with changes in glucose transporter expression of maternal peripheral blood granulocytes and monocytes. Am J Reprod Immunol 48: 110-116, 2002
73. Bilban M, Bühler LK, Head S, Desoye G, Quaranta V. Defining signal thresholds in DNA microarrays: exemplary application for invasive cancer. Biomed Central Genomics 2002 3:19-33.
74. Korgun ET, Dohr G, Desoye G, Demir R, Kayisli ÜA, Hahn T. Expression of insulin, insulin-like growth factor I and glucocorticoid receptor in rat uterus and embryo during decidualization, implantation and organogenesis. Reproduction 125, 1-10, 2003
75. Wadsack C, Hammer A, Levak-Frank S, Desoye G, Sattler W, Malle E. The selective uptake from high-density lipoprotein by human frist trimester and term trophoblast. A preferential routing for cholesteryl ester supply during fetal development? Placenta in press

Submitted:

1. Mandl M, Haas J, Nöhammer G, Desoye G. Differential glucocorticoid effects on proliferation and invasion of human first trimester trophoblast models. Human Reproduction
2. Halwachs G, Weiss U, Desoye G. CMV infections of human trophoblast. Placenta
   

Monographs:

1. Trophoblast Research Vol 14: Trophoblast Biology and Immunology; ed. Desoye G, Miller R, Sibley C; 2000

Chapters

1. *Desoye G. The human placenta in gestational diabetes. In: Gestational Diabetes, eds Weiss, PAM and Coustan, DR. 1987. Springer, Wien. 72-86.
2. *Desoye G, Weiss PAM, Hofmann HMH. Der plazentare Insulinrezeptor bei Gestationsdiabetes. In: Probleme der perinatalen Medizin Bd 15: Kohlenhydratstoffwechselstörungen und Schwangerschaft, ed. Weiss, PAM. 1987., Maudrich, Wien. 27-30.
   
3. Lang I, Desoye G, Schöninkle E, Pabst MA (2000) Scanning electron microscopic (SEM) investigations underline the heterogeneity of endothelial cells from human term placenta and umbilical cord. In: Proceedings of the 12th European Congress on Electron Microscopy. Biological Sciences, Vol. 1 (Eds.: S. Cech, R. Janisch) pp.: B599-B600. EUREM12, Brno, Czech Republic.
   
4. Desoye G, Hauguel de-Mouzon S, Shafrir E. The human placenta in diabetes. In: Textbook of Diabetic Pregnancy 2002 in press
   

Various

1. Desoye G. Conference report: 2nd International Symposium on Diabetes and Pregnancy in the 90's, Jerusalem, 19-23 March 1995. Placenta 1995; 16: 561-563.
   
2. Blaschitz A, Weiss U, Desoye G, Dohr G. Die Plazenta: Quelle biomedizinischer Forschung. mta Spektrum 2001; 2: 57-62
   
3. Lala P, Desoye G. Signal Transductions: Variants on Developmental Control from Implantation to Delivery. Placenta 22 (Suppl A): S98-S100 (2001)

Invited reviews:

1. *Desoye G. Insulin receptors and insulin effects in the human placenta. Curr Topics Exp Endocrinol 1993; 1: 77-89
2. *Desoye G, Shafrir E. Placental metabolism and its regulation in health and diabetes. Molec Asp Med 1994; 15: 505-682.
3. *Desoye G, Shafrir E. The placenta in diabetic pregnancy. Diabetes Rev 1996; 4: 70-89.
4. *Hahn T, Desoye G. Ontogeny of glucose transport systems in the placenta and its progenitor tissues. Early Pregnancy: Biology and Medicine 1996; 2: 168-182
5. *Desoye G, Hartmann M, Jones CJP, Wolf HJ, Kohnen G, Kosanke G, Kaufmann P. Location of insulin receptors in the placenta and its progenitor tissues. Microscopic Res Technics 1997; 38: 63-75.
6. Schneider H, Desoye G. Strukturelle und funktionelle Veränderungen in der Plazenta bei Diabetes in der Schwangerschaft. Gynäkologe 1998; 31: 173-181.
7. Desoye G. Transport across the human placenta. Acta med. Croatica 55 (Suppl 1) 2001, 30-34.
8. Desoye G, Hahn T. Structrual and functional derangements of the placenta in diabetes. Acta med. Croatica; in press

Back to Graz Page

Christian WADSACK

Department of Obstetrics and Gynecology
Karl-Franzens-University of Graz
Auenbruggerplatz 14
A-8036 Graz
Tel: +43 316 385 2476
E-Mail: christian.wadsack@uni-graz.at

Address	Heinrichstrasse 64a/3, A - 8010 Graz, Austria Tel.: 0316/832137
Date and place of birth	23. January 1968, Knittelfeld, Austria
Nationality	Austria/Hungary
Marital status	Married, three children
Education	High School (Knittelfeld, BRG-Kärntnerstraße), 1978 -1986
	Military Service October 1986 - October 1987
Academic qualifications	Institute of Organic Chemistry, Karl-Franzens University Graz, Supervisor: Prof. Dr. H. Junek
Studies 1987 – 1989 1989 –1998 Title of diploma thesis	Chemistry M.Sci., Technical University Graz, Austria M.Sci., Karl-Franzens University Graz, Austria “Synthesis and Characterisation of 2,6-Di[(2,6-di{[3-(N-maleoyl)propanoyl]amino} hexanoyl)amino]hexanacid as a new maleinimide compound for synthesis of chemoimmuno-conjugates”
1998-2002	PhD, Karl-Franzens University Graz, Austria Institute of Medical Biochemistry and Medical Molecular Biology, Karl-Franzens University Graz, Supervisor: Prof. Dr. E. Malle
Title of PhD thesis:	“Scavenger receptor class B, type I dependent uptake of high density lipoprotein associated cholesterylesters by human (i) first trimester and term trophoblasts, (ii) trophoblast-like choriocarcinoma cells and (iii) malignant and non malignant liver cells.”
October, 2002 to present	Postdoctoral Investigator at the Department of Obstetrics and Gynecology (Prof. Dr. G. Desoye, Karl-Franzens University Graz). The Project is financed by the EU (PERILIP grant). Topic : fatty-acid metabolism of the human placenta
Training	1.) Synthesis in monoclonal antibodies Training at the Dept. Histology and Embryology (Dr. Hammer) Karl-Franzens University Graz, December 1998 2.) Histochemical techniques Training at the Dept. Histology and Embryology (Dr. Hammer) Karl-Franzens University Graz, February 1999 3.) Biochemical techniques Training at the Dept. Med. Biochemistry (Dr. Malle) Karl-Franzens University Graz, March - June 1999

Publications

1. Selective cholesteryl ester uptake from high density lipoprotein by human first trimester and term villous trophoblast cells
   Christian WADSACK, Astrid HAMMER, Sanja LEVAK-FRANK, Gernot DESOYE, Wolfgang SATTLER, and Ernst MALLE
   PLACENTA in press
2. Trophoblast-like human choriocarcinoma cells serve as a suitable in vitro model for selective cholesteryl ester uptake from high density lipoproteins
   Christian WADSACK, Andelko HRZENJAK, Astrid HAMMER, Birgit HIRSCHMUGL, Sanja LEVAK-FRANK, Gernot DESOYE, Wolfgang SATTLER, and Ernst MALLE
   European Journal of Biochemistry in press
   
3. Scavenger receptor class B, type I on non-malignant and malignant human epithelial cells mediates cholesteryl ester-uptake from high density lipoproteins
   Christian WADSACK, Birgit HIRSCHMUGL, Astrid HAMMER, Sanja LEVAK-FRANK, Wolfgang SATTLER, and Ernst MALLE
   The International Journal of Biochemistry & Cell Biology in press

Back to Graz Page

Nicole Prutsch

Ursula Hiden

Department of Obstetrics and Gynecology
Karl-Franzens-University of Graz
Auenbruggerplatz 14
A-8036 Graz
Tel: +43 316 385 2476
E-Mail: ursula.hiden@uni-graz.at